Abstract
At the Seventh International Symposium on Peripheral Arterial Chemoreceptors we reported that close arterial infusion of dopamine (20–50 μg.min-1) induced either no changes or reductions in extracellular K+([K+]0) and Ca++ ([Ca++]0) activities in the cat carotid body (O’Regan and Acker, 1984). Further experimentation has confirmed these findings although in occasional trials [Ca++]0 elevations rather than reductions accompanied dopamine admininstration. As the major action of dopamine is considered to be inhibition of chemoreceptor activity we felt it would be of interest to compare its effects on [K+]0 and [Ca++]0 with those associated with agents which predominantly excite chemoreceptor discharges such as cyanide, acetylcholine and hypoxic hypoxaemia.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Acker, H. (1978). Pflugers Archiv., 375, 229–232.
Biscoe, T.J. (1971). Physiol Rev., 51, 437–495.
Delpiano, M.A. and Acker, H. (1981). Pflugers Archiv. Suppl., 391, R 48.
Dufau, E., Acker, H. and Sylvester, D. (1982). Med.Prog.Tech., 9, 33–38.
Fidone, S.J., Gonzalez, C. and Yoshizaki, K. (1982). J.Physiol., 333, 93–110.
Gronblad, M., Akerman, K.E. and Eranko, O. (1979). Anat.Rec., 195, 387–396.
Gronblad, M., Akerman, K.E. and Eranko, O. (1980). Brain Res., 189, 576–581.
McQueen, D.S. (1983). In, Physiology of the Peripheral Arterial Chemoreceptors. H. Acker and R.G. O’Regan (eds.), Elsevier, Science Publications, pp 149–196.
O’regan, R.G. and Acker, H. (1984). In, The Peripheral Arterial Chemoreceptors. D.J. Pallot (ed.), Croom Helm, pp 75-83.
Roumy, M. and Leitner, L-M, (1977). In, Chemoreception in the Carotid Body. H. Acker et al (eds.). Springer Verlag, pp 257-263.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1987 J.A. Ribeiro and David J. Pallot
About this chapter
Cite this chapter
O’Regan, R.G., Acker, H. (1987). Effects of Cyanide and Acetylcholine on Extracellular K+ and Ca++ Activities in the Cat Carotid Body. In: Ribeiro, J.A., Pallot, D.J. (eds) Chemoreceptors in Respiratory Control. Springer, Dordrecht. https://doi.org/10.1007/978-94-015-1155-1_11
Download citation
DOI: https://doi.org/10.1007/978-94-015-1155-1_11
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-015-1157-5
Online ISBN: 978-94-015-1155-1
eBook Packages: Springer Book Archive