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Molecular mechanisms of chemosensory transduction: gustation and olfaction

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Fish Chemoreception

Part of the book series: Fish & Fisheries Series ((FIFI,volume 6))

Abstract

Understanding of vertebrate chemoreception has been greatly aided by several aquatic models. The fishes in particular are well suited as biological models because they often possess specific, sensitive and readily accessible chemosensory organs. The ability to define receptor specificity and sensitivity — using classical receptor binding techniques — has permitted a critical evaluation of the several transduction sequences that follow the initial receptor binding step. It is now clear that the peripheral specificity hypothesized with neurophysiological techniques is present at the receptor membrane level and that these receptor events are coupled to changes in intracellular ionic activity via either GTP-binding regulatory protein stimulation (inhibition) of second messengers or direct translocation of ions via stimulus-gated ion channel receptors. The recent progress in characterizing these sequences in fish chemosensory systems has stimulated the search for similar mechanisms in mammalian chemoreception.

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  1. J. G. Brand
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  2. R. C. Bruch
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Editors and Affiliations

  1. Department of Fisheries and Oceans, Freshwater Institute, Canada

    Toshiaki J. Hara

  2. Department of Zoology, University of Manitoba, Winnipeg, Manitoba, R3T 2N6, Canada

    Toshiaki J. Hara

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Brand, J.G., Bruch, R.C. (1992). Molecular mechanisms of chemosensory transduction: gustation and olfaction. In: Hara, T.J. (eds) Fish Chemoreception. Fish & Fisheries Series, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-2332-7_7

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  • DOI: https://doi.org/10.1007/978-94-011-2332-7_7

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