Abstract
Within any class of substituted aromatic acid or base it is usually found that the acidic dissociation constant will vary in much the same way as that of the corresponding derivative in any other class. In most cases, these changes in acid strength, āpK a, produced by a substituent in a meta- or para-position can be predicted by the Hammett equation.
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Ā© 1981 D. D. Perrin, Boyd Dempsey and E. P. Serjeant
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Perrin, D.D., Dempsey, B., Serjeant, E.P. (1981). Prediction of pK a Values for Phenols, Aromatic Carboxylic Acids and Aromatic Amines. In: pK a Prediction for Organic Acids and Bases. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-5883-8_5
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DOI: https://doi.org/10.1007/978-94-009-5883-8_5
Publisher Name: Springer, Dordrecht
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