Abstract
The most widespread and common human filarial parasite is Wuchereria bancrofti, which currently infects around 100 million people in the humid tropics. The most common vector in towns is the ubiquitous tropical house mosquito, Culex quinquefasciatus; however, anopheline mosquitoes are important vectors in rural areas. The other major filarial parasite of humans transmitted by mosquitoes is Brugia malayi, which is patchily distributed in India and Southeast Asia. Mosquito-borne filariasis, widely known for the disfiguring elephantiasis which occurs in a proportion of cases, is still a major public health problem in the tropics. Considerable research effort has been expended on developing improved methods of chemotherapy, on immunodi-agnosis and on understanding the factors that influence transmission by mosquitoes.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Ash, L.R. and Riley, J.M. (1970) Development of Brugia pahangi in the jird, Meriones unguiculatus, with notes on infections in other rodents. J. Parasit.56, 962–968.
Bosworth, W., Sullivan, J.J. and Chernin, E. (1976) Infective larvae of Brugia: Escape from mosquitoes into water and subsequent oral infectivity in jirds. Am. J. Trop. Med. Hyg.25, 700–703.
Crans, W.J. (1971) Mass separation of infective stage larvae from suspected mosquito vectors. Preliminary results of tests conducted in coastal Tanzania. WHO/FIL/71.96 (mimeographed document).
Curtis, C.F., Ellis, D.S., Doyle, P.E., Ramji, B.D., Hill, N., Irungu, L.W. and Townson, H. (1983) Susceptibility of aposymbiotic Culex quinquefasciatus to Wuchereria bancrofti. J. Invert. Pathol.41, 214–223.
Denham, D.A., Dennis, D.T., Ponnudurai, T., Nelson, G.S. and Guy, F. (1971) Comparison of a counting chamber and thick smear methods of counting microfilariae. Trans. R. Soc. Trop. Med. Hyg.65, 521–526.
Gerberg, E.J., Barnard, D.R. and Ward, R.A. (1994) Manual for mosquito rearing and experimental techniques. American Mosquito Control Association Bulletin No. 5 (revised.),
Jin, L.Z. and Xu, J.J. (1991) Observations on the development of quantitatively inoculated Brugia malayi microfilariae in Anopheles sinensis and Culex quinquefasciatus. Chung Kuo Chi Sheng Chung Hsueh Yu Chi Sheng Chung Ping Tsa Chih9, 106–109 (in Chinese).
Kilama, W.L. (1976) Variation in susceptibility of East African Aedes aegypti strains to Wuchereria bancrofti infection. E. African J. Med. Res.3, 127–132.
Klowden, M.J. (1981) Infection of Aedes aegypti with Brugia pahangi administered by enema: results of quantitative infection and loss of infective larvae during blood feeding. Trans. R. Soc. Trop. Med. Hyg.75, 354–358.
Lindsay, S J. and Denham, D.A. (1986) The ability of Aedes aegypti to survive and transmit infective larvae of Brugia pahangi over successive blood meals. J. Helminth.60, 159–168.
McCall, J.W., Malone, J.B., Ah, H.S. and Thompson, P.E. (1973) Mongolian jirds (Meriones unguiculatus) infected with Brugia pahangi by the intraperitoneal route: a rich source of developing larvae, adult filariae and microfilariae. J. Parasitol.59, 436.
Macdonald, W.W. (1971) The maintenance of vectors of filariasis. In Isolation and Maintenance of Parasites in vivo (A.E.R. Taylor and R. Muller, eds). Symp. Brit. Soc. Parasitol.9, 123–149.
Macdonald, W.W. (1976) Mosquito genetics in relation to filarial infections. In Genetic aspects of Host-Parasite Relationships (A.E.R. Taylor and R. Muller, eds). Symp. Brit. Soc. Parasitol.14, 1–24.
Macdonald, W.W. and Ramachandran, C.P. (1965) The influence of the gene fm (filarial susceptibility, Brugia malayi) on the susceptibility of Aedes aegypti to seven strains of Brugia, Wuchereria and Dirofilaria. Ann. Trop. Med. Parasitol.59, 64–73.
Macdonald, W.W. and Sheppard, P.M. (1965) Cross-over values in the sex chromosomes of the mosquito Aedes aegypti and evidence of the presence of inversions. Ann. Trop. Med. Parasitol.59, 74–87.
Minjas, J.N. and Townson, H. (1980) The successful cryopreservation of microfilariae with hydroxyethyl starch as cryoprotectant. Ann. Trop. Med. Parasitol.74, 571–573.
Munstermann, L.E. (1990) Gene map of the yellow fever mosquito Aedes (Stegomyia) aegypti. In Genetic Maps. Locus Maps of Complex Genomes (S.J. O’Brien, ed.), 5th edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
Paige, C.J. and Craig, G.B. (1975) Variation of filarial susceptibility among East African populations of Aedes aegypti. J. Med. Ent.12, 485–493.
Rodriguez, P.H. and Craig, G.B. (1973) Susceptibility to Brugia pahangi in geographic strains of Aedes aegypti. Am. J. Trop. Med. Hyg.22, 53–61.
Schrater, A.F., Rossignol, P.A., Hamill, B., Piessens, W.F. and Spielman, A. (1982) Brugia malayi microfilariae from the peritoneal cavity of jirds vary in their ability to penetrate the mosquito midgut. Am. J. Trop. Med. Hyg.31, 292–296.
Southgate, B.A. (1973) Studies on filariasis in the Pacific: 1. A field trial of a counting-chamber technique for the determination of microfilarial rates and densities. South-east Asian J. Trop. Med. Hyg.4, 172–178.
Terwedow and Rodriquez (1973) Development of Brugia pahangi in male mosquitoes. J. Parasitol.59, 222–223.
Townson, H. (1974) The development of Brugia pahangi in male Aedes aegypti of ‘refractory’ genotype. Ann. Trop. Med. Parasitol.68, 239–240.
Townson, H. and Chaithong, U. (1991) Mosquito host influences on development of filariae. Ann. Trop. Med. Parasitol.85, 149–163.
Trpis, M. (1994) Aedes (Gymnometopa) mediovittatus (Diptera: Culicidae) as an experimental vector of Brugia pahangi and B.malayi (Spiruridae: Filariidae). J. Med. Ent.31, 442–444.
Wade, J.O. (1976) A new design of membrane feeder incorporating an electrical blood stirring device. Ann. Trop. Med. Parasitol.70, 113–120.
Yates, J.A., Schmitz, K.A. and Rajan, T.V. (1994) Infectivity and normal development of third stage Brugia malayi maintained in vitro. J. Parasitol.80, 891–894.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Chapman & Hall
About this chapter
Cite this chapter
Townson, H. (1997). Infection of mosquitoes with filaria . In: Crampton, J.M., Beard, C.B., Louis, C. (eds) The Molecular Biology of Insect Disease Vectors. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1535-0_9
Download citation
DOI: https://doi.org/10.1007/978-94-009-1535-0_9
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-7185-7
Online ISBN: 978-94-009-1535-0
eBook Packages: Springer Book Archive