Abstract
Trypanosoma brucei rhodesiense and T. b. gambiense are salivarian trypanosomes (subgenus Trypanozoon) which are major pathogens of humans causing, respectively, the acute (Rhodesian) and chronic (Gambian) forms of sleeping sickness in Africa. Both trypanosome species are transmitted during feeding via the salivary glands of tsetse flies, both sexes of which are exclusively haematophagous. Trypanosomes must overcome two obstacles in completing their life-cycle in the fly: (i) they must establish in the midgut and (ii) mature from midgut to mammalian infective forms in the salivary glands.
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Maudlin, I. (1997). Infection of tsetse with Trypanosoma brucei rhodesiense and T. b. gambiense. In: Crampton, J.M., Beard, C.B., Louis, C. (eds) The Molecular Biology of Insect Disease Vectors. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1535-0_12
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DOI: https://doi.org/10.1007/978-94-009-1535-0_12
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