Abstract
Since the introduction of modern imaging modalities into the diagnosis of liver diseases, the detection of small mass lesions in the liver has become possible and the early diagnosis of hepatocellular carcinoma (HCC) has been established. Regular check-ups with examinations of tumor markers, serum alpha-fetoprotein and ultrasonography (US) for chronic hepatitis and liver cirrhosis are indispensable for making an early diagnosis of HCC. Although conventional diagnostic imaging and radiographic modalities, such as ultrasound, X-ray computed tomography (CT), magnetic resonance (MR), and angiography, are effectively used in detecting small mass lesions of the liver, they cannot discriminate small HCC from benign mass lesions such as large regenerative nodules (LRNs) of cirrhosis. Thus, histological examinations of small mass lesions by percutaneous biopsy under ultrasound image control have become imperative for reaching a final diagnosis of HCC and designing an appropriate treatment regimen.
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© 1992 Springer-Verlag Tokyo
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Ohto, M., Kondo, F., Ebara, M. (1992). Pathology, diagnosis, and treatment for small liver cancer. In: Tobe, T., et al. Primary Liver Cancer in Japan. Springer, Tokyo. https://doi.org/10.1007/978-4-431-68177-9_36
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DOI: https://doi.org/10.1007/978-4-431-68177-9_36
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68179-3
Online ISBN: 978-4-431-68177-9
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