Summary
An antibody to the calcium binding protein, calbindin D28k (CaBP), was used to study the number and size of CaBP immunoreactive (CaBP-Ir) neurones in the cerebral cortex and the nucleus basalis of Meynert (nbM) of postmortem human brains from controls and from patients with Alzheimer-type dementia (ATD).
Compared to the controls, the number and size of CaBP-Ir neurones in the cerebral cortex and the nbM were reduced in the ATD.
These findings suggest that CaBP containing neurones are damaged in ATD.
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© 1990 Springer-Verlag Wien
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Ichimiya, Y., Arai, H., Iizuka, R., Emson, P.C., Mountjoy, C.Q. (1990). Calbindin immunoreactive neurones in Alzheimer-type dementia. In: Maurer, K., Riederer, P., Beckmann, H. (eds) Alzheimer’s Disease. Epidemiology, Neuropathology, Neurochemistry, and Clinics. Key Topics in Brain Research. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3396-5_18
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DOI: https://doi.org/10.1007/978-3-7091-3396-5_18
Publisher Name: Springer, Vienna
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