Zusammenfassung
Die Atempumpe generiert den inspiratorischen und exspiratorischen Luftfluss durch Veränderungen des intrathorakalen Drucks in Zusammenspiel mit der Weite der oberen Atemwege. Ihre Bestandteile sind der Thorax, die thorakale Muskulatur, das Zwerchfell, die abdominelle Muskulatur, die Atemhilfsmuskulatur und die Muskulatur der oberen Atemwege. Durch Erkrankungen der Thoraxwand, neuromuskuläre Erkrankungen und Erkrankungen, welche die Atempumpe indirekt beeinträchtigen, wird die Ventilation gestört und es kommt zum ventilatorischen Versagen mit Anstieg des paCO2. Dieser ist im Schlaf und insbesondere im REM-Schlaf am ausgeprägtesten. Bei der Diagnostik von Störungen der Atempumpe spielen Spirometrie, Bodyplethysmographie und die bildgebende Darstellung des Zwerchfells eine wichtige Rolle. Die korrekte Diagnostik von Störungen der Atempumpe ist bedeutsam, da – bei ätiologisch nicht zu behebender ventilatorischer Insuffizienz – die Beatmungstherapie zum Einsatz kommt, wodurch bei vielen Erkrankungen der Atempumpe die Überlebenszeit, aber auch die Lebensqualität erheblich gesteigert werden können.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Literatur
Abouassaly CT et al (2010) Postoperative neuromuscular blocker use is associated with higher primary fascial closure rates after damage control laparotomy. J Trauma Acute Care Surg 69(3):557–561
Allen SM et al (1985) Fall in vital capacity with posture. Br J Dis chest 79:267–271
Aumüller G et al (2014) Duale Reihe Anatomie. Thieme, Stuttgart
Bach JR (2017) Noninvasive respiratory management of patients with neuromuscular disease. Ann Rehabil Med 41(4):519
Bach JR, Gonçalves MR (2006) Pulmonary rehabilitation in neuromuscular disorders and spinal cord injury. Rev Port de Pneumologia 12(1):S27–S44
Bach JR et al (2004) Oximetry and indications for tracheotomy for amyotrophic lateral sclerosis*. Chest 126(5):1502–1507
Bach JR et al (2008) Lung insufflation capacity in neuromuscular disease. Am J Phys Med Rehabil 87(9):720–725
Barreiro E et al (2015) Guidelines for the evaluation and treatment of muscle dysfunction in patients with chronic obstructive pulmonary disease. Arch Bronconeumol (English Edition) 51(8):384–395
Barrios C et al (2008) Successful management of occult pneumothorax without tube thoracostomy despite positive pressure ventilation. Am Surg 74(10):958–961
Barwing J et al (2013) Electrical activity of the diaphragm (EAdi) as a monitoring parameter in difficult weaning from respirator: a pilot study. Crit Care 17(4):R182
Bjorck M, Wanhainen A (2014) Management of abdominal compartment syndrome and the open abdomen. Eur J Vasc Endovasc Surg 47(3):279–287
Boentert M, Young P (2016) Schlaf und Atmung bei neuromuskulären Erkrankungen. Klin Neurophysiol 47(03):151–162
Boentert M et al (2018) Prevalence of sleep apnoea and capnographic detection of nocturnal hypoventilation in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 89(4):418–424
Boon AJ et al (2013) Two-dimensional ultrasound imaging of the diaphragm: quantitative values in normal subjects. Muscle Nerve 47(6):884–889
Bourke SC et al (2006) Effects of non-invasive ventilation on survival and quality of life in patients with amyotrophic lateral sclerosis: a randomised controlled trial. Lancet Neurol 5(2):140–147
Budweiser S et al (2006) Impact of ventilation parameters and duration of ventilator use on non-invasive home ventilation in restrictive thoracic disorders. Respiration 73(4):488–494
Buyse B et al (2003) Treatment of chronic respiratory failure in kyphoscoliosis: oxygen or ventilation? Eur Respir J 22(3):525–528
Caro CG, Dubois AB (1961) Pulmonary function in kyphoscoliosis. Thorax 16(3):282
Celik S et al (2010) Long-term results of diaphragmatic plication in adults with unilateral diaphragm paralysis. J cardiothorac surg 5(1):111
Chatwin M et al (2017) Airway clearance techniques in neuromuscular disorders: a state of the art review. Respir Med 136:98–110
Chhajed PN (2016) Utility of transcutaneous capnography for optimization of non-invasive ventilation pressures. J Clin Diagn Res: JCDR 10(9):OC06
Chouri-Pontarollo N et al (2007) Impaired objective daytime vigilance in obesity-hypoventilation syndrome: impact of noninvasive ventilation. Chest 131(1):148–155
Davis JN (1967) Phrenic nerve conduction in man. J Neurol Neurosurg Psychiatry 30(5):420
De Bruin PF et al (1997) Diaphragm thickness and inspiratory strength in patients with Duchenne muscular dystrophy. Thorax 52(5):472–475
De Troyer A (1997) Effect of hyperinflation on the diaphragm. Eur Respir J 10(3):708–713
De Troyer A (2011) The action of the canine diaphragm on the lower ribs depends on activation. J Appl Physiol 111(5):1266–1271
De Troyer A, Wilson TA (2016) Action of the diaphragm on the rib cage. J Appl Physiol 121(2):391–400
Dos Santos Yamaguti WP et al (2008) Air trapping: the major factor limiting diaphragm mobility in chronic obstructive pulmonary disease patients. Respirology 13(1):138–144
Engdahl O et al (1993) Chest radiograph–a poor method for determining the size of a pneumothorax. Chest 103(1):26–29
Estenne M, De Troyer A (1985) Relationship between respiratory muscle electromyogram and rib cage motion in tetraplegia. Am Rev Respir Dis 132(1):53–59
Fayssoil A et al (2018) Diaphragm: pathophysiology and ultrasound imaging in neuromuscular disorders. J neuromuscul Dis 5(1):1–10
Ferreira JC et al (2017) Neurally Adjusted Ventilatory Assist (NAVA) or Pressure Support Ventilation (PSV) during spontaneous breathing trials in critically ill patients: a crossover trial. BMC Pulm Med 17(1):139
Fromageot C et al (2001) Supine fall in lung volumes in the assessment of diaphragmatic weakness in neuromuscular disorders. Arch Phys Med Rehabil 82(1):123–128
Gazala S et al (2012) Diaphragmatic plication offers functional improvement in dyspnoea and better pulmonary function with low morbidity. Interact CardioVasc Thorac Surg 15(3):505–508
Greenburg DL et al (2009) Effects of surgical weight loss on measures of obstructive sleep apnea: a meta-analysis. Am J Med 122(6):535–542
Gregg I, Nunn AJ (1973) Peak expiratory flow in normal subjects. Br Med J 3(5874):282–284
Hedenstierna G, Larsson A (2012) Influence of abdominal pressure on respiratory and abdominal organ function. Curr Opin Crit Care 18(1):80–85
Hsu CW, Sun SF (2014) Iatrogenic pneumothorax related to mechanical ventilation. World J Crit Care Med 3(1):8
Huttl TP et al (2004) Laparoscopic diaphragmatic plication: long-term results of a novel surgical technique for postoperative phrenic nerve palsy. Surg Endosc Other Interv Tech 18(3):547–551
Huttmann SE et al (2014) Techniques for the Measurement and Monitoring of Carbon Dioxide in the Blood. Ann Am Thorac Soc 11(4):645–652
Jenkins JA et al (2016) Phrenic nerve conduction studies as a biomarker of respiratory insufficiency in amyotrophic lateral sclerosis. Amyotrophic Lateral Scler Frontotemporal Degeneration 17(3–4):213–220
Jeong JH, Yoo WG (2015) Effects of air stacking on pulmonary function and peak cough flow in patients with cervical spinal cord injury. J Phys Ther Sci 27(6):1951–1952
Johnson G (1996) Traumatic pneumothorax: is a chest drain always necessary? Emerg Med J 13(3):173–174
Kabitz HJ et al (2014) Messung der Atemmuskelfunktion. Pneumologie 68(05):307–314
Kang SW, Bach JR (2000a) Maximum insufflation capacity. Chest 118(1):61–65
Kang SW, Bach JR (2000b) Maximum insufflation capacity: vital capacity and cough flows in neuromuscular disease. Am J Phys Med Rehabil 79(3):222–227
Kantarci F et al (2004) Normal diaphragmatic motion and the effects of body composition: determination with M-mode sonography. J Ultrasound Med 23(2):255–260
Kartal M et al (2011) The value of ETCO2 measurement for COPD patients in the emergency department. Eur J Emerg Med 18(1):9–12
Kirkpatrick AW et al (2010) Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation? Crit Care 14(4):232
Kokatnur L, Rudrappa M (2018) Diaphragmatic Palsy. Diseases 6(1):16
Koo P et al (2017) The maximal expiratory-to-inspiratory pressure ratio and supine vital capacity as screening tests for diaphragm dysfunction. Lung 195(1):29–35
Kwon S et al (2015) Usefulness of phrenic latency and forced vital capacity in patients with ALS with latent respiratory dysfunction. Clin Neurophysiol 126(7):1421–1426
Larsen R, Ziegenfuß T (2013) Beatmung. Springer, Berlin
Lattuada M, Hedenstierna G (2006) Abdominal lymph flow in an endotoxin sepsis model: influence of spontaneous breathing and mechanical ventilation. Crit Care Med 34(11):2792–2798
Lechtzin N et al (2006) Supramaximal inflation improves lung compliance in subjects with amyotrophic lateral sclerosis. Chest 129(5):1322–1329
Lefrant JY et al (2002) Regional blood flows are affected differently by PEEP when the abdomen is open or closed: an experimental rabbit model. Canadian Journal of Anesthesia 49(3):302
Leiner GC et al (1963) Expiratory peak flow rate: standard values for normal subjects. Use as a clinical test of ventilatory function. Am Rev Respir Dis 88(5):644–651
Marti S et al (2010) Predictors of mortality in chest wall disease treated with noninvasive home mechanical ventilation. Respir Med 104(12):1843–1849
McKenzie DK et al (2009) Respiratory muscle function and activation in chronic obstructive pulmonary disease. J Appl Physiol 107(2):621–629
Mogalle K et al (2016) Quantification of diaphragm mechanics in pompe disease using dynamic 3D MRI. PLoS ONE 11(7):e0158912
Oczenski W (2008) Atem und Atemhilfen. Thieme, Stuttgart
Onders RP et al (2014) Extended use of diaphragm pacing in patients with unilateral or bilateral diaphragm dysfunction: a new therapeutic option. Surgery 156(4):776–786
Onders RP et al (2018) Completed FDA feasibility trial of surgically placed temporary diaphragm pacing electrodes: A promising option to prevent and treat respiratory failure. Am J Surg 215(3):518–521
Patel DS et al (2009) Work of breathing during SIMV with and without pressure support. Arch Dis Child 94(6):434–436
Pinto S, de Carvalho M (2017) Correlation between forced vital capacity and slow vital capacity for the assessment of respiratory involvement in amyotrophic lateral sclerosis: a prospective study. Amyotrophic Lateral Scler Frontotemporal Degeneration 18(1–2):86–91
Pinto S et al (2016) Ultrasound for assessment of diaphragm in ALS. Clin Neurophysiol 127(1):892–897
Piper AJ, Grunstein RR (2010) Big breathing: the complex interaction of obesity, hypoventilation, weight loss, and respiratory function. J Appl Physiol 108(1):199–205
Priewe J, Tümmers D (2007) Kompendium Vorklinik – GK1. Springer, Heidelberg
Ptok M (2014) Zwerchfell: Aufbau und Zwerchfelldurchtrittsstellen. Sprache Stimme Gehör 38:45–46
Ragette R et al (2002) Patterns and predictors of sleep disordered breathing in primary myopathies. Thorax 57(8):724–728
Rollnik JD et al (2017) Prolonged weaning during early neurological and neurosurgical rehabilitation: S2k guideline published by the Weaning Committee of the German Neurorehabilitation Society (DGNR). Der Nervenarzt 88(6):652–674
Rosier S et al (2014) The accuracy of transcutaneous PCO2 in subjects with severe brain injury: a comparison with end-tidal PCO2. Respir Care 59(8):1242–1247
Sancho J et al (2007) Predictors of ineffective cough during a chest infection in patients with stable amyotrophic lateral sclerosis. Am J Respir Crit Care Med 175(12):1266–1271
Sarwal A et al (2013) Neuromuscular ultrasound for evaluation of the diaphragm. Muscle Nerve 47(3):319–329
Schellhas V et al (2018) Upper airway obstruction induced by non-invasive ventilation using an oronasal interface. Sleep and Breathing 22(3):781–788
Schlenker E et al (1997) Effect of noninvasive ventilation on pulmonary artery pressure in patients with severe kyphoscoliosis. Medizinische Klinik (Munich, Germany: 1983) 92:40–44
Schwarz SB (2017) Continuous non-invasive PCO2 monitoring in weaning patients: transcutaneous is advantageous over end-tidal PCO2. Respirology 22(8):1579–1584
Severgnini P et al (2013) Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function. Anesthesiol: J Am Soc Anesthesiol 118(6):1307–1321
Sharp JT et al (1986) Diaphragmatic responses to body position changes in obese patients with obstructive sleep apnea. Am Rev Respir Dis 133(1):32–37
Shneerson JM, Simonds AK (2002) Noninvasive ventilation for chest wall and neuromuscular disorders. Eur Respir J 20(2):480–487
Sieck GC et al (2013) Mechanical properties of respiratory muscles. Compr Physiol 3(4):1533–1567
Siobal MS (2016) Monitoring exhaled carbon dioxide. Respir Care 61(10):1397–1416
Sturm R (2007) Increases in morbid obesity in the USA: 2000–2005. Public Health 121(7):492–496
Tebb ZD et al (2010) An argument for the conservative management of small traumatic pneumathoraces in populations with high prevalence of HIV and tuberculosis: an evidence-based review of the literature. Int J Emerg Med 3(4):391
Van Lunteren E, Strohl KP (1986) The muscles of the upper airways. Clin Chest Med 7(2):171
Van Marcke C et al (2015) CO2 measurement for the early differential diagnosis of pulmonary embolism-related shock at the emergency department: a case series. Respir Med Case Rep 16:106–108
Walker SP et al (2018) Conservative management in traumatic pneumothoraces: an observational study. Chest 153(4):946–953
Wen S et al (2015) Lung MRI and impairment of diaphragmatic function in Pompe disease. BMC Pulm Med 15(1):54
Wilson TA (2016) Respiratory mechanics. Springer, Basel
Windisch W et al (2017) Nichtinvasive und invasive Beatmung als Therapie der chronischen respiratorischen Insuffizienz – Revision 2017. Pneumologie 64(04):207–240
Wu W et al (2017) Transdiaphragmatic pressure and neural respiratory drive measured during inspiratory muscle training in stable patients with chronic obstructive pulmonary disease. Int J Chronic Obstructive Pulm Dis 12:773
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Groß, M., Summ, O. (2020). Die Atempumpe und ihre Störungen. In: Groß, M. (eds) Neurologische Beatmungsmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-59014-0_4
Download citation
DOI: https://doi.org/10.1007/978-3-662-59014-0_4
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-59013-3
Online ISBN: 978-3-662-59014-0
eBook Packages: Medicine (German Language)