Zusammenfassung
Die respiratorische Insuffizienz ist definiert als schwerwiegende Störung des pulmonalen Gasaustauschs. Ist v. a. der Austausch von Sauerstoff (O2) betroffen, spricht man von einer hypoxischen Form des respiratorischen Versagens, während bei der hyperkapnischen respiratorischen Insuffizienz v. a. die Elimination für Kohlendioxid (CO2) alteriert ist. Grundlagen und Ursachen der unterschiedlichen Formen der respiratorischen Insuffizienz sind Gegenstand dieses Kapitels.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
Literatur
Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, Fan E, Camporota L, Slutsky AS (2012) Acute respiratory distress syndrome: the Berlin Definition. JAMA 307:2526–2533
Bersten AD, Edibam C, Hunt T, Moran J (2002) Incidence and mortality of acute lung injury and the acute respiratory distress syndrome in three Australian States. Am J Respir Crit Care Med 165:443–448
Luhr OR, Antonsen K, Karlsson M, Aardal S, Thorsteinsson A, Frostell CG, Bonde J (1999) Incidence and mortality after acute respiratory failure and acute respiratory distress syndrome in Sweden, Denmark, and Iceland. The ARF Study Group. Am J Respir Crit Care Med 159:1849–1861
Rubenfeld GD, Caldwell E, Peabody E, Weaver J, Martin DP, Neff M, Stern EJ, Hudson LD (2005) Incidence and outcomes of acute lung injury. N Engl J Med 353:1685–1693
Hernu R, Wallet F, Thiolliere F, Martin O, Richard JC, Schmitt Z, Wallon G, Delannoy B, Rimmele T, Demaret C, Magnin C, Vallin H, Lepape A, Baboi L, Argaud L, Piriou V, Allaouchiche B, Aubrun F, Bastien O, Lehot JJ, Ayzac L, Guerin C (2013) An attempt to validate the modification of the American-European consensus definition of acute lung injury/acute respiratory distress syndrome by the Berlin definition in a university hospital. Intensive Care Med 39:2161–2170
Villar J, Blanco J, Del CR, Andaluz-Ojeda D, Diaz-Dominguez FJ, Muriel A, Corcoles V, Suarez-Sipmann F, Tarancon C, Gonzalez-Higueras E, Lopez J, Blanch L, Perez-Mendez L, Fernandez RL, Kacmarek RM (2015) Assessment of PaO2/FiO2 for stratification of patients with moderate and severe acute respiratory distress syndrome. BMJ Open 5:e006812
Gao L, Barnes KC (2009) Recent advances in genetic predisposition to clinical acute lung injury. Am J Physiol Lung Cell Mol Physiol 296:L713–L725
Fujishima S (2014) Pathophysiology and biomarkers of acute respiratory distress syndrome. J Intensive Care 2:32
Aschner Y, Zemans RL, Yamashita CM, Downey GP (2014) Matrix metalloproteinases and protein tyrosine kinases: potential novel targets in acute lung injury and ARDS. Chest 146:1081–1091
Sakka SG (2013) Extravascular lung water in ARDS patients. Minerva Anestesiol 79:274–284
Glas GJ, Van Der Sluijs KF, Schultz MJ, Hofstra JJ, Van Der Poll T, Levi M (2013) Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome. J Thromb Haemost 11:17–25
Pelosi P, D’Andrea L, Vitale G, Pesenti A, Gattinoni L (1994) Vertical gradient of regional lung inflation in adult respiratory distress syndrome. Am J Respir Crit Care Med 149:8–13
Bull TM, Clark B, McFann K, Moss M (2010) Pulmonary vascular dysfunction is associated with poor outcomes in patients with acute lung injury. Am J Respir Crit Care Med 182:1123–1128
Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA (2002) Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 346:1281–1286
Chesnutt AN, Matthay MA, Tibayan FA, Clark JG (1997) Early detection of type III procollagen peptide in acute lung injury. Pathogenetic and prognostic significance. Am J Respir Crit Care Med 156:840–845
Cheung AM, Tansey CM, Tomlinson G, Diaz-Granados N, Matte A, Barr A, Mehta S, Mazer CD, Guest CB, Stewart TE, Al-Saidi F, Cooper AB, Cook D, Slutsky AS, Herridge MS (2006) Two-year outcomes, health care use, and costs of survivors of acute respiratory distress syndrome. Am J Respir Crit Care Med 174:538–544
Oeyen SG, Vandijck DM, Benoit DD, Annemans L, Decruyenaere JM (2010) Quality of life after intensive care: a systematic review of the literature. Crit Care Med 38:2386–2400
Heyland DK, Groll D, Caeser M (2005) Survivors of acute respiratory distress syndrome: relationship between pulmonary dysfunction and long-term health-related quality of life. Crit Care Med 33:1549–1556
Wheeler AP, Bernard GR, Thompson BT, Schoenfeld D, Wiedemann HP, deBoisblanc B, Connors AF Jr, Hite RD, Harabin AL (2006) Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med 354:2213–2224
Gattinoni L, Caironi P, Pelosi P, Goodman LR (2001) What has computed tomography taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med 164:1701–1711
Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, Rothenberg P, Zhu J, Sachdeva R, Sonnad S, Kaiser LR, Rubinstein NA, Powers SK, Shrager JB (2008) Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 358:1327–1335
Bruells CS, Marx G, Rossaint R (2014) Ventilator-induced diaphragm dysfunction: clinically relevant problem. Anaesthesist 63:47–53
Ramsay M, Hart N (2013) Current opinions on non-invasive ventilation as a treatment for chronic obstructive pulmonary disease. Curr Opin Pulm Med 19:626–630
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2019 Springer-Verlag GmbH Deutschland, ein Teil von Springer Nature
About this chapter
Cite this chapter
Dembinski, R. (2019). Respiratorische Insuffizienz. In: Rossaint, R., Werner, C., Zwißler, B. (eds) Die Anästhesiologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-54507-2_129
Download citation
DOI: https://doi.org/10.1007/978-3-662-54507-2_129
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-54505-8
Online ISBN: 978-3-662-54507-2
eBook Packages: Medicine (German Language)