Skip to main content

CUP-Tumoren

  • Chapter
PET/CT-Atlas

Zusammenfassung

»Cancer of unknown primary« (CUP) ist charakterisiert als eine Tumorerkrankung mit (zunächst) unbekanntem bzw. vielfach sehr spät detektiertem Primärtumor. Die Heilungschancen stehen in Abhängigkeit von dem Zeitpunkt, zu dem dieser identifiziert und behandelt werden kann sowie von der Anzahl der (resektablen) Metastasen. Erfahrungsgemäß sind in der Gruppe der CUP-Tumoren die Kopf-Hals-Tumoren die größte Tumorentität. Für die Behandlungsplanung und die Abschätzung der Prognose des Patienten ist es erforderlich, nicht nur die gesamte Tumorausdehnung, sondern auch die Herkunft der Metastasen zu ermitteln. Die PET/CT leistet bei der Primärdiagnostik von CUP-Syndromen einen entscheidenden Beitrag.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 299.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Literatur

  1. Assar OS, Fischbein NJ, Caputo GR et al. (1999) Metastatic head and neck cancer: role and usefulness of FDG PET in locating occult primary tumors. Radiology 210: 177–181

    Article  Google Scholar 

  2. Bristow RE, del Carmen MG, Pannu HK et al. (2003) Clinically occult recurrent ovarian cancer: patient selection for secondary cytoreductive surgery using combined PET/CT. Gynecol Oncol 90: 519–528

    Article  PubMed  Google Scholar 

  3. Burell SC, Van den Abbeele AD (2018) 2-deoxy-2-[F-18]fluoro-Dglucose- positron emission tomography of the head and neck: an atlas of the normal uptake and variants. Mol Imaging Biol 7: 244–256

    Article  Google Scholar 

  4. Czernin J, Auerbach (2018) Clinical PET/CT imaging: promises and misconceptions. Nuklearmedizin 44 (suppl 1): S18–23

    Google Scholar 

  5. Gambhir SS, Czernin J, Schwimmer J et al. (2001) A tabulated summary of the FDG PET literature. J Nucl Med (suppl) 42: 1–93

    Google Scholar 

  6. Greco FA, Hainsworth JD (1993) Cancer of unknown primary site. In: Devita VT Jr, Hellma NS, Rosenberg SA (Hrsg) Cancer: principles and practice of oncology. Lippincott-Raven, Philadelphia, S 2072–2092

    Google Scholar 

  7. Gutzeit A, Antoch G, Kühl H et al. (2018) Unknown primary tumors: detection with dual modality PET/CT-initial experience. Radiology 234: 227–234

    Article  Google Scholar 

  8. Hör G, Mantaka P (1998) Application of PET in clinical oncology. In: Limouris GS, Shukla SK, Bender HF, Biersack HJ (Hrsg) Radionuclides for oncology—current status and future aspects. Mediterra, Athens, S 107–111

    Google Scholar 

  9. Israel O, Mor M, Guralnik L et al. (2004) Is 18F-FDG PET/CT useful for imaging and management of patients with suspected and occult recurrence of cancer? J Nucl Med 45: 2045–2051

    PubMed  Google Scholar 

  10. Kazmierczak PM, Nikolaou K, Rominger A, Graser A, Reiser MF, Cyran CC (2014) Radiological diagnostics in CUP syndrome. Radiologe 54(2): 117–123

    Article  CAS  PubMed  Google Scholar 

  11. Lee JR, Kim JS, Roh JL, Lee JH, Baek JH, Cho KJ, Choi SH, Nam SY, Kim SY (2015) Detection of Occult Primary Tumors in Patients with Cervical Metastases of Unknown Primary Tumors: Comparison of (18)F FDG PET/CT with Contrast-enhanced CT or CT/MR Imaging-Prospective Study. Radiology 274(3): 764–771

    Article  PubMed  Google Scholar 

  12. Makaiova I, Vesely J, Kovacova S et al. (2002) False positive uptake of 18FDG-fluorodeoxyglukose in the axillary brown fat lipoma (hibernoma)—case report. EANM, Abstract

    Google Scholar 

  13. Manolidis S, Donald PJ, Volk P, Pounds TR (1998) The use of positron emission tomography scanning in occult and recurrent head and neck cancer. Acta Otolaryngol 534 (suppl): 1–11

    Article  CAS  Google Scholar 

  14. Mantaka P, Hertel A, Adams S et al. (1998) Contribution of PETFDG in the diagnosis of cancer of unknown primary. In: Limouris GS, Shukla SK, Bender HF, Biersack HJ (Hrsg) Radionuclides for oncology—current status and future aspects. Mediterra, Athens, S 121–131

    Google Scholar 

  15. Regelink G, Brouwer J, de Bree R et al. (2002) Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities. Eur J Nucl Med 29: 1024–1030

    Article  CAS  Google Scholar 

  16. Scott CL, Kudaba I, Stewart JM et al. (2018) The utility of 2-deoxy- 2-[F-18]fluoro-D-glucose positron emission tomography in the investigation of patients with disseminated carcinoma of unknown primary origin. Mol Imaging Biol 7: 236–243

    Article  Google Scholar 

  17. Sengupta MS, Lee SJ, Hoh CK et al. (1995) Utility and cost effectiveness of FDG whole body PET in patients with unknown primary malignancies. J Nucl Med 36: 56

    Google Scholar 

  18. Wahl RL (2004) Why nearly all PET of abdominal and pelvic cancers will be performed as PET/CT. J Nucl Med 45 (suppl 1): S81–95

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Mohnike, W., Hör, G., Lampe, M. (2016). CUP-Tumoren. In: Mohnike, W., Hör, G., Hertel, A., Schelbert, H. (eds) PET/CT-Atlas. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-48842-3_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-48842-3_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-48841-6

  • Online ISBN: 978-3-662-48842-3

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics