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Bacterial γ-Poly(glutamic Acid)

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Biopolymers from Renewable Resources

Part of the book series: Macromolecular Systems — Materials Approach ((MACROSYSTEMS))

Abstract

γ-Poly(glutamic acid), γ-PGA, is a bacterially synthesized water soluble nylon. It can be classified as a pseudo-poly(amino acid) which contains only glutamate repeat units. γ-PGA differs from proteins, however, in that the glutamate repeat units are polymerized by a ribosome-independent process. Furthermore, the glutamate repeat units are linked between the α-amino and γ-carboxylic acid functional groups (see below) [1].

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References

  1. Troy FA (1973) J Biol Chem 248 (1): 305

    CAS  Google Scholar 

  2. Hanby WE, Rydon HN (1946) Biochem 40: 297

    CAS  Google Scholar 

  3. Thorne CB, Gomez CG, Noyes HE, Housewright RD (1954) J Bacteriol 68 (3): 307

    CAS  Google Scholar 

  4. Torii M (1959) J Biochem 46 (2): 189

    Google Scholar 

  5. Hara T, Ueda S (1982) Agricul Biol Chem 46 (9): 2275

    Article  CAS  Google Scholar 

  6. Kramar E (1921) Centr Bakteriol Parasitenk Abt I Orig 88: 401

    Google Scholar 

  7. Ivanovics G, Bruckner V (1937) Z Immunitatsforsch 25: 250

    CAS  Google Scholar 

  8. Ivanovics G (1965) In: Florkin M, Stotzm EH (eds) Comprehensive biochemistry: lipids and amino acids and related compounds. Elsevier, New York, vol 6, p 286

    Google Scholar 

  9. Ezepchuk YV (1968) Zh Microbiol Epidemiol Immunobiol 45: 110

    CAS  Google Scholar 

  10. Housewright RD (1962) In: Gunsalus IC, Stanier RY (eds) The bacteria. Academic Press, New York, vol. III, p 389

    Google Scholar 

  11. Nitecki DE, Goodman JW (1971) In: Weinstein B (ed.) Chemistry and biochemistry of amino acids, peptides, and proteins. Marcel Dekker, New York, vol. I, p 87

    Google Scholar 

  12. Troy FA (1982) In: Kleinkauf H, von Dohren H (eds) Peptide antibiotics biosynthesis and functions. Walter de Gruyter, New York, p 49

    Google Scholar 

  13. Buchanan RE, Gibbons NE (eds.) Bergey’s manual of determinative bacteriology, 8th edn. William Wilkins, Baltimore, p 530

    Google Scholar 

  14. Vasantha N, Freese E (1978) J Gen Micro 112: 329

    Article  Google Scholar 

  15. Foerster HF (1972) J Bacteriol 111 (2): 437

    CAS  Google Scholar 

  16. Bernlohr RW (1967) J Bacteriol 93 (3): 1031

    CAS  Google Scholar 

  17. Leonard CG, Housewright RD, Thorne CG (1958) J Bacteriol 76: 499

    CAS  Google Scholar 

  18. Lafferty RM, Korstko B, Korsatko W (1984) In: Rose AH, Tempest DW (eds) Advances in microbial physiology. Academic Press, Cleveland OH, vol 25, chap 6, p 136

    Google Scholar 

  19. McLean RJC, Beauchemin D, Clapham L, Beveridge TJ (1990) Appl Enrion Micro 56 (12): 3671

    CAS  Google Scholar 

  20. Birrer GA, Cromwick A-M, Gross RA (1994) Int J Biol Macromol 16 (5): 265

    Article  CAS  Google Scholar 

  21. Kubota H, Matsunobu T, Uotani K, Takebe H, Satoh A, Tanaka T, Taniguchi M (1993) Biosci Biotech Biochem 57 (7): 1212

    Article  CAS  Google Scholar 

  22. Cromwick A-M, Gross RA (1995) Int J Biol Macromol 17 (5): 259

    Article  CAS  Google Scholar 

  23. Goto A, Kunioka M (1992) Biosc Biotech Biochem 56 (7): 1031

    Article  CAS  Google Scholar 

  24. Sawa S, Murao S, Murakawa T, Omata S (1971) Nippon Nôgeikagaku Kaishi 45 (3): 123

    Google Scholar 

  25. Cromwick A-M, Birrer GA, Gross RA (1996) Biotechnol Bioeng 50: 222

    Article  CAS  Google Scholar 

  26. Murao S, Murakawa T, Omata S (1969) Nippon Nôgeikagaku Kaishi 43 (9): 595

    Article  CAS  Google Scholar 

  27. Murao S, Sawa S, Murakawa T, Omata S (1971) Nippon Nôgeikagaku Kaishi 45 (3): 118

    Article  CAS  Google Scholar 

  28. Fujii H (1963) Nippon Nôgeikagaku Kaishi 37 (6): 346

    Article  CAS  Google Scholar 

  29. Fujii H (1963) Nippon Nôgeikagaku Kaishi 37 (7): 407

    Article  CAS  Google Scholar 

  30. Fujii H (1963) Nippon Nôgeikagaku Kaishi 37 (8): 474

    Article  CAS  Google Scholar 

  31. Fujii H (1963) Nippon Nôgeikagaku Kaishi 37 (10): 619

    Article  CAS  Google Scholar 

  32. Fujii H (1963) Nippon Nôgeikagaku Kaishi 37 (10): 619

    Article  CAS  Google Scholar 

  33. Saito I, Iso N, Mizuno H, Kaneda H, Suyama Y, Kawamura S, Osawa S (1974) Agr Biol Chem 38 (10): 1941

    Article  CAS  Google Scholar 

  34. Ward RM, Anderson RF, Dean FK (1963) Biotech Bioeng V: 41

    Article  Google Scholar 

  35. Cheng C, Asada Y, Aida T (1989) Agric Biol Chem 53 (9): 2369

    Article  CAS  Google Scholar 

  36. Thorne CB, Leonard CG (1958) J Biol Chem 233 (5): 1109

    CAS  Google Scholar 

  37. Torii M (1959) J Biochem 46 (4): 513

    CAS  Google Scholar 

  38. Utsumi S, Torii M, Kurimura H, Yamamuro H, Amano T (1958) Biken’s J 1: 201

    CAS  Google Scholar 

  39. Utsumi S, Torii M, Kurimura H, Yamamuro H, Amano T (1959) Biken’s J 2: 165

    CAS  Google Scholar 

  40. Sawa S, Murakawa T, Murao S, Ornata S (1973) Nippon Nogeikagaku Kaishi 47 (3): 159

    Article  CAS  Google Scholar 

  41. Troy FA (1973) J Biol Chem 248 (1): 316

    CAS  Google Scholar 

  42. Thorne CB (1956) In: Symposia of the Society for General Microbiology. University Press, Cambridge, p 68

    Google Scholar 

  43. Thorne CB, Gomez CG, Molnar DM (1956) Bacteriol Proc Soc Am Bacteriol 107

    Google Scholar 

  44. Cromwick A-M, Gross RA (1995) Can J Microbiol 41: 902

    Article  CAS  Google Scholar 

  45. Grossowicz N, Wainfan E, Borek E, Waelsch H (1950) J Biol Chem 186: 111

    Google Scholar 

  46. Stumpf PK, Loomis NE (1950) Arch Biochem 25: 451

    CAS  Google Scholar 

  47. Hanes CS, Hird FJR, Isherwood FA (1950) Nature 166: 288

    Article  CAS  Google Scholar 

  48. Hanes CS, Hird FJR, Isherwood FA (1952) Biochem J 51: 25

    CAS  Google Scholar 

  49. Williams WJ, Thorne CB (1954) J Biol Chem 210: 203

    CAS  Google Scholar 

  50. Williams WJ, Litwin J, Thorne CB (1955) J Biol Chem 212: 427

    CAS  Google Scholar 

  51. Leonard CG, Housewright RD (1963) Biochim Biophys Acta 73: 530

    Article  CAS  Google Scholar 

  52. Housewright RD, Thorne CB (1950) J Bacteriol 60: 89

    CAS  Google Scholar 

  53. Thorne CB, Gomez CG, Housewright RD (1955) J Bacteriol 69: 357

    CAS  Google Scholar 

  54. Gardner JM, Troy FA (1979) J Biol Chem 254 (14): 6262

    CAS  Google Scholar 

  55. Volcani BE, Margalith P (1957) J Bacteriol 74: 646

    CAS  Google Scholar 

  56. Bruckner V, Kajtar M, Kovacs J, Nagy H, Wein J (1958) Tetrahedron 2: 211

    Article  CAS  Google Scholar 

  57. Tanaka T, Hiruta O, Futamura T, Uotani K, Satoh A, Taniguchi M, Oi S (1993) Biosci Biotech Biochem 57: 2148

    Article  CAS  Google Scholar 

  58. Torii M, Kurimura O, Utsumi S, Nozu H, Amano T (1959) Biken’s Journal 2: 265

    CAS  Google Scholar 

  59. Shah DT, McCarthy SP, Gross RA (1992) Polym Prep Am Chem Soc 33 (2): 488

    CAS  Google Scholar 

  60. Gross RA, McCarthy SP, Shah DT (1995) US Patent 5, 378, 807

    Google Scholar 

  61. Kubota H, Nambu Y, Endo TJ (1993) Polym Sci Part A: Polym Chem 31: 2877

    Article  CAS  Google Scholar 

  62. Borbély M, Nagasaki Y, Borbély J, Fan K, Bhogle A, Sevoian M (1994) Polym Bull 32: 127

    Article  Google Scholar 

  63. Tsubokawa N, Inagaki M, Endo T (1993) J Polym Sci Part A: Polym Chem 31: 563

    Article  CAS  Google Scholar 

  64. Swift G (1993) Accounts Chem Res 26: 105

    Article  CAS  Google Scholar 

  65. Ratner BD, Horbett TA (1995) In: Cooper SL, Bamford CH, Tsuruta T (eds) Polymer biomaterials in solution, as interfaces and as solids. VSP, Utrecht, The Netherlands, p xxiii

    Google Scholar 

  66. Hikichi K, Hirouki T, Konno A (1990) Polymer 22 (2): 103

    Article  CAS  Google Scholar 

  67. Rosenthal WS, O’Connell DJ, Axelrod DR, Bovarnick M (1956) J Exptl Med 103: 667

    Article  CAS  Google Scholar 

  68. Kessler BJ, DiGrado CJ, Benante C, Bovarnick M, Silber RH, Zambito AJ (1955) Proc Soc Exptl Biol Med 88: 651

    CAS  Google Scholar 

  69. Kream J, Borek BA, DiGrado J, Bovernick M (1954) Arch Biochem Biophys 53: 333

    Article  CAS  Google Scholar 

  70. Bovernick M, Eisenberg F, O’Connell D, Victor J, Owades P (1954) J Biol Chem 207: 593

    Google Scholar 

  71. Crescenzi V, D’Alagni M, Dentini M, Maltei B (1996) In: Ottenbrite RM, Huang SJ, Park K (eds) Hydrogels and biodegradable polymers for bioapplications. American Chemical Society, Washing DC, p 233

    Google Scholar 

  72. Choi HJ, Kunioka M (1995) Radiat Phys Chem 46: 175

    Article  CAS  Google Scholar 

  73. Kunioka M, Choi HJ (1996) J Environ Polym Deg 4 (2): 123

    Article  CAS  Google Scholar 

  74. Farrell RE, Gross RA, McCarthy SP, unpublished results

    Google Scholar 

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Authors
  1. R. A. Gross
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Editors and Affiliations

  1. Department of Chemical Engineering, Biotechnology Center, Tufts University, 4 Colby Street, 02155, Medford, MA, USA

    David L. Kaplan

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© 1998 Springer-Verlag Berlin Heidelberg

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Gross, R.A. (1998). Bacterial γ-Poly(glutamic Acid). In: Kaplan, D.L. (eds) Biopolymers from Renewable Resources. Macromolecular Systems — Materials Approach. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03680-8_8

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  • DOI: https://doi.org/10.1007/978-3-662-03680-8_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-08341-9

  • Online ISBN: 978-3-662-03680-8

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