Abstract
The goal of any anti-cancer therapy is to eradicate malignant cells and prevent their regrowth. The extent of cell kill is dependent upon the sensitivity of the cells and the dose of cytotoxic therapy administered. For many treatment modalities the dose limiting factor is myelosuppression. Hence, it is often impossible to give the maximum desired dose since patients would succumb to bone marrow aplasia and associated complications such as hemorrhage and infection. This problem can be ameliorated by the infusion of marrow following cytotoxic therapy.
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© 1992 Springer-Verlag Berlin Heidelberg
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Deeg, H.J., Klingemann, HG., Phillips, G.L. (1992). Introduction. In: A Guide to Bone Marrow Transplantation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97374-1_1
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DOI: https://doi.org/10.1007/978-3-642-97374-1_1
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