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Teratogenicity of Hormones In Utero

  • Chapter
Hormone Toxicity in the Newborn

Part of the book series: Monographs on Endocrinology ((ENDOCRINOLOGY,volume 31))

  • 42 Accesses

Abstract

Many drugs taken by pregnant and nursing women might affect the baby (see Hutchings, 1989). Drug teratogenicity was not a major concern until the thalidomide tragedy in the early 1960’s. The tranquilizer, produced in Germany (by Chemie Grünenthal) and improperly tested, was widely prescribed in Europe to combat “morning sickness” in pregnancy. The birth of hundreds of infants with phocomelia, poorly developed limbs (the “seal flipper” deformity), was the result. The drug sold even in the face of mounting reports of the malformation, hitherto one of the rarest. Only when the US Food and Drug Administration did not clear the drug for the US market was thalidomide banned in Europe.

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  1. The College of Staten Island of the City University of New York, Staten Island, New York, USA

    Fred A. Kincl Ph.D., DSc., FRSC (Professor Emeritus)

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  1. Fred A. Kincl Ph.D., DSc., FRSC
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Kincl, F.A. (1990). Teratogenicity of Hormones In Utero. In: Hormone Toxicity in the Newborn. Monographs on Endocrinology, vol 31. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83794-4_3

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  • DOI: https://doi.org/10.1007/978-3-642-83794-4_3

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