Skip to main content
SpringerLink
Log in

Proteins

  • Chapter
Physical Approaches to Biological Evolution

  • 224 Accesses

Abstract

At the molecular level of life processes we encounter informational biopoly-mers, i.e. macromolecules of proteins and nucleic acids. The role of nucleic acids is “legislative”: they are responsible for the biosynthesis of proteins. The role of proteins is “executive”. They can do everything; they are only incapable of self-synthesis. In other words, all functions of a cell, organism or species are determined at the molecular level by proteins. The structure of proteins and their functional dynamics are thus subject to natural selection.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Reference

  1. Volkenstein, M. (1994): Biophysics, 2nd edn. ( Mir Publishers and The American Institute of Physics, translated by Artavaz Beknazarov, Moscow and New York )

    Google Scholar 

  2. Volkenstein, M. (1963): Configurational Statistics of Polymeric Chains ( Interscience Pub-lishers, New York )

    Google Scholar 

  3. Birstein, T., Ptitsyn, 0. (1966): Conformations of Macromolecules ( Interscience Publishers, New York )

    Google Scholar 

  4. Flory, P. (1969): Statistical Mechanics of Chain Molecules ( Interscience Publishers, New York )

    Google Scholar 

  5. Lifshitz, I., Grosberg, A., Khokhlov, A. (1978): Rev. Mod. Phys. 50, 683–713

    MathSciNet  ADS  Google Scholar 

  6. Grosberg, A., Khokhlov, A. (1989): Statistical Physics of Macromolecules ( Nauka, Moscow ) (in Russian)

    Google Scholar 

  7. Golovanov, I., Sobolev, V., Volkenstein, M. (1991): Biopolymers ( Nauka, Moscow ) (in Russian)

    Google Scholar 

  8. Levitt, M., Chothia, C. (1976): Nature 261, 552–8

    ADS  Google Scholar 

  9. Chothia, C. (1984): Ann. Rev. Biochem. 53, 537–72

    Google Scholar 

  10. Ptitsyn, O. (1985): J. Biosciences (India) 8, 1–13

    Google Scholar 

  11. Chou, K., Maggiore, G., Némethy, G., Scheraga, H. (1988): Proc. Nat. Acad. Sci. USA 85, 4295–9

    ADS  Google Scholar 

  12. Golovanov, I., Tsygankova, I., Nautshitel, V., Volkenstein, M. (1989): Doklady Akad. Nauk SSSR 309, 633–7; Molek. Biol. 25, 133–43 (1991)

    Google Scholar 

  13. Schrödinger, E. (1945): What is Life?( Cambridge University Press, Cambridge )

    Google Scholar 

  14. Frauenfelder, H., Parak, F., Young, R. (1988): Ann. Rev. Biophys., Biophys. Chem. 17, 451

    Google Scholar 

  15. Iben, E. et al. (1989): Phys. Rev. Letters 62, 1916–9

    ADS  Google Scholar 

  16. Frauenfelder, H., Steinbach, P., Young, R. (1989): Chemica Scripta 29A

    Google Scholar 

  17. Frauenfelder, H. (1989): Nature 338, 623–4

    ADS  Google Scholar 

  18. Frauenfelder, H. (1989): Internat. J. Quantum Chem. 35, 711–5

    Google Scholar 

  19. Goldansky, V., Krupiansky, Y., Flerov, V. (1983): Doklady Akad. Nauk SSSR 272, 978

    Google Scholar 

  20. Volkenstein, M., Ptitsyn, O. (1955): Doklady Akad. Nauk SSSR 103, 795; J. Technical Phys. 26, 2204 (1956)

    Google Scholar 

  21. Volkenstein, M., Sharonov, Y. (1961): Vysokomolek. Soedin. 3, 1740–5; (1962) 4, 917–21

    Google Scholar 

  22. Polyakov, K. et al. (1987): Kristallografia 32, 918–26

    Google Scholar 

  23. Volkenstein, M. (1971): Izv. Akad. Nauk SSSR. Ser. Biol. 805–14

    Google Scholar 

  24. Volkenstein, M. (1982): Vestnik Akad. Nauk SSSR 10 56–63

    Google Scholar 

  25. Volkenstein, M., Golovanov, I., Sobolev, V. (1982): Molecular Orbitals in Enzymology ( Nauka, Moscow ) (in Russian)

    Google Scholar 

  26. Volkenstein, M. (1982): Physics and Biology ( Academic Press, New York )

    Google Scholar 

  27. Volkenstein, M. (1981): J. Theor. Biol. 89, 45–51

    Google Scholar 

  28. Volkenstein, M. (1972): J. Theor. Biol. 34, 193–5

    Google Scholar 

  29. Shaitan, K., Rubin, A. (1985): Biofizika 30, 517–26

    Google Scholar 

  30. Onuchi, J., Wolynes, P. (1988): J. Phys. Chem. 92, 6495–503

    Google Scholar 

  31. Krakoviak, M. et al. (1975): Doklady Akad. Nauk SSSR 224, 873–6

    Google Scholar 

  32. Krakoviak, M. et al. (1975): Izv. Akad. Nauk SSSR. Ser. Fiz. 39, 2354–8

    Google Scholar 

  33. Krakoviak, M. et al. (1978): Vysokomolek. Soedin. 1320, 129–32

    Google Scholar 

  34. Volkenstein, M., Sharonov, Y. (1977): Priroda 5, 30–41

    Google Scholar 

  35. Sharonov, Y., Pismensky, V., Yarmola, E. (1988): Molek. Biol. 22, 1272–83; 1491–506

    Google Scholar 

  36. Sharonov, Y., Pismensky, V., Yarmola, E. (1988): FEBS Letters 235, 63–6

    Google Scholar 

  37. Dreinsicke, D., Schulz, G. (1988): J. Mol. Biol. 203, 1021–8

    Google Scholar 

  38. Sinev, M., Razgulyaev, O., Timchenko, A., Ptitsyn, O. (1989): Eur. J. Biochem. 180, 61–6

    Google Scholar 

  39. Williams, J., Clegg, H., Hutch, J. (1961): J. Mol. Biol. 3, 532–40

    Google Scholar 

  40. Finkelstein, A., Ptitsyn, O. (1971): J. Mol Biol. 62, 613–24

    Google Scholar 

  41. Poroikov, V., Esipova, N., Tumanian, V. (1976): Biofizika 21, 397–400

    Google Scholar 

  42. Ptitsyn, O. (1984): Molek. Biol. 18,574–90; (1985) J. Mol. Structures 123,45–65

    Google Scholar 

  43. Ptitsyn, O., Finkelstein, A. (1980): Quart. Rev. Biophys. 13, 339–86

    Google Scholar 

  44. Chan, H.S., Dill, K. (1989): J. Chem. Phys. 90, 492–509

    MathSciNet  ADS  Google Scholar 

  45. Chan, H.S., Dill, K. (1990): Proc. Nat. Acad. Sci. USA 87, 6388–92

    ADS  Google Scholar 

  46. Chan, H.S., Dill, K. (1989): Macromolecules 22, 4559–73

    ADS  Google Scholar 

  47. Lau, K.F., Dill, K. (1989): Macromolecules 22, 3986–97; (1990): Proc. Nat. Acad. Sci. USA 87, 638–42

    ADS  Google Scholar 

  48. Lau, K.F., Dill, K. (1989): Macromolecules 22, 3986–97; (1990): Proc. Nat. Acad. Sci. USA 87, 638–42

    ADS  Google Scholar 

  49. Shakhnovich, E., Gutin, A. (1989): Formation of a Unique Structure in Polypeptide Chains. A Theoretical Investigation with the Aid of the Replica Approach. Preprint (Pushchino) (in Russian).

    Google Scholar 

  50. Shakhnovich, E., Gutin, A. (1989): J. Phys. A: Math. Gen. 22, 1647–59

    ADS  Google Scholar 

  51. Shakhnovich, E., Gutin, A. (1989): J. Phys. France 50, 1843–50

    Google Scholar 

  52. Shakhnovich, E., Gutin, A. (1989): J. Phys. France 50, 1843–50

    Google Scholar 

  53. Shakhnovich, E., Gutin, A. (1990): Nature 346 773

    ADS  Google Scholar 

  54. Lesk, A., Chothia, C. (1980): J. Mol. Biol. 136, 225–70

    Google Scholar 

  55. Bashford, D., Chothia, C., Lesk, A. (1987): J. Mol. Biol. 196, 199–216

    Google Scholar 

  56. Spivak, V. (1986): Molek. Biol. 20, 789–97

    Google Scholar 

  57. Imai, K. et al. (1989): Protein Sequences and Data Analysis 2, 81–6

    Google Scholar 

  58. Dickerson, R. (1980): Scientific American 242, 3, 98–111

    Google Scholar 

  59. Chipens, G., Polevaja, L., Veretennikova, N., Krikis, A. (1980): The Structure and Functions of Low-Molecular Peptides ( Zinatne, Riga ) (in Russian)

    Google Scholar 

  60. Crick, F., Barnett, L., Brenner, S., Watts-Tobin, R. (1961): Nature 192, 1227–31

    ADS  Google Scholar 

  61. Volkenstein, M. (1981): Zhur. Obshch. Biol. 42, 680–6

    Google Scholar 

  62. Anfinsen, C.B. (1959): The Molecular Basis of Evolution (J. Wiley and Sons, New York; Chapman and Hall, London )

    Google Scholar 

  63. Kimura, M. (1983): The Neutral Theory of Molecular Evolution ( Cambridge University Press, Cambridge )

    Google Scholar 

  64. Altukhov, Y. (1990): Genetic Processes in Populations ( Nauka, Moscow ) (in Russian)

    Google Scholar 

  65. Ptitsyn, O. (1981): FEBS Letters 131, 197–203

    Google Scholar 

  66. Montelione, G., Wutrich, K., Nice, E., Burgess, A., and Scheraga H. (1987): Proc. Nat. Acad. Sci. USA 84, 5226–30

    ADS  Google Scholar 

  67. Gibson, K., Scheraga, H. (1988): In Structure and Expression, Vol. 1: From Proteins to Ribosomes,ed. M. Sarma and R. Sarma (Adenine Press, Gulderband, New York)

    Google Scholar 

  68. Gibson, K., Chin, S., Pincus, M., Clement, E., Scheraga, H. (1986): In Lecture Notes in Chemis-try, Vol. 44: Supercomputer Simulations in Chemistry, ed. M. Dupuis ( Springer-Verlag, Berlin )

    Google Scholar 

  69. Vasquez, M., Scheraga, H. (1988): J. Biomol. Structure and Dynamics 5, 705, 757

    Google Scholar 

  70. Montelione, G., Scheraga, H. (1989): Accounts of Chemical Research 22, 70–6

    Google Scholar 

  71. Ripoll, D., Scheraga, H. (1988): Biopolymers 27, 1283–90

    Google Scholar 

  72. Scheraga, H. (1989): Chemica Scripta 20, 20–5

    Google Scholar 

  73. Dickerson, R. Geis, I. (1969): The Structure and Action of Proteins (Harper and Row Publishers, New York, Evanston, London)

    Google Scholar 

  74. Miller, S., Janin, J., Lesk, A., Chothia, C. (1987): J. Molec. Biol. 196, 641–50

    Google Scholar 

  75. Chothia, C., Lesk, A. (1986): EMBO Journal 5, 823–9

    Google Scholar 

  76. Chothia, C., Lesk, A. (1987): Cold Spring Harbor Symposia. Quart. Biol. 52, 399–405

    Google Scholar 

  77. Perutz, M. (1983): Molec. Biol. Evol. 1, 1–28

    Google Scholar 

  78. Volkenstein, M. (1966): Biochim. Biophys. Acta 119, 421–6

    Google Scholar 

  79. Volkenstein, M. (1977): Molecular Biophysics (Academic Press, New York, San Francisco and London).

    Google Scholar 

  80. Creighton, T., Darby, N. (1989): Trends in Biochem. Sciences 14, 319–24

    Google Scholar 

  81. Bode, W., Greyling, H., Huber, R., Otlewski, J., Wilusz, T. (1989): FEBS Letters 242, 285–91

    Google Scholar 

  82. Creighton, T., Charles, I. (1987): Cold Spring Harbor Symposia. Quart. Biol. 52, 511–9

    Google Scholar 

  83. Ptitsyn, O., Volkenstein, M. (1986): J. Biomol. Structure and Dynamics 4, 137–56

    Google Scholar 

  84. Doolittle, R. (1979): In The Proteins, Vol. 4 ( Academic Press, New York ) pp. 2–118

    Google Scholar 

  85. Jacob, F. (1977): Science 196, 1161–6

    ADS  Google Scholar 

  86. Jacob, F. (1985): In Evolution from Molecules to Men, ed. D.S. Bendall ( Cambridge University Press, Cambridge )

    Google Scholar 

  87. Eisenberg, D. et al. (1986): Proteins 1, 16–22

    Google Scholar 

  88. Ho, S., De Grado, W. (1987): J. Amer. Chem. Soc. 109, 6751–8

    Google Scholar 

  89. Lear, J., Wasserman, Z., De Grado, W. (1988): Science 240, 1173–81

    ADS  Google Scholar 

  90. Regan, L., De Grado, W. (1988): Science 241, 976–8

    ADS  Google Scholar 

  91. De Grado, W., Wasserman, Z., Lear, J. (1988): Science 243, 622–8

    Google Scholar 

  92. Matsumara, M., Matthews, B. (1988): Science 243, 792–4

    ADS  Google Scholar 

  93. Warshel, A., Sussman, F., Hwang, J.-K. (1988): J. Molec. Biol. 201, 139–59

    Google Scholar 

  94. Novotny, J., Rashin, A., Bruccoleri, R. (1988): Proteins 4, 19–30

    Google Scholar 

  95. Russel, A., Fersht, A. (1987): Nature 328, 496–500

    ADS  Google Scholar 

  96. Egami, F. (1975): J. Biochem. 77, 1165–75

    Google Scholar 

  97. Williams, R. (1985): Eur. J. Biochem. 150, 231–48

    Google Scholar 

  98. Vallee, B., Williams, R. (1968): Proc. Nat. Acad. Sci. USA 59, 498–505

    ADS  Google Scholar 

  99. Vallee, B., Williams, R. (1968): Chemistry in Britain 4, 398–505

    Google Scholar 

  100. Berg, J. (1985): Cold Spring Harbor Symposia. Quant. Biol. 52, 579–85

    Google Scholar 

  101. Coon, M., White, R. (1980): In Metal Ion Activation of Dioxygen, ed. T. Spire ( Wiley, New York )

    Google Scholar 

  102. Lewin, R. (1982): Science 217, 42–3

    ADS  Google Scholar 

  103. Chothia, C., Lesk, A. (1982): J. Molec. Biol. 160, 309–23

    Google Scholar 

  104. Fox, S., ed. (1965): The Origin of Prebiological Systems and of Their Molecular Matrices ( Academic Press, New York )

    Google Scholar 

  105. McAnliffe, C., ed. (1975): Techniques and Topics in Bioinorganic Chemistry ( Macmillan, New York )

    Google Scholar 

  106. Eichhorn, G., ed. (1975): Inorganic Biochemistry, Vols. 1, 2 (Elsevier, Amsterdam )

    Google Scholar 

  107. Hughes, M. (1981): The Inorganic Chemistry of Biological Processes (John Wiley and Sons, Chichester, New York, Brisbane and Toronto )

    Google Scholar 

  108. Volkenstein, M. (1982): Molek. Biol. 16, 901–29

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Moscow, Russia

    Professor Mikhail V. Volkenstein

Authors
  1. Professor Mikhail V. Volkenstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Volkenstein, M.V. (1994). Proteins. In: Physical Approaches to Biological Evolution. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-78788-1_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-78788-1_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-78790-4

  • Online ISBN: 978-3-642-78788-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation