Abstract
Competition experiments were performed among 33 selected monoclonal antibodies (mAbs) to the cytoplasmic side of all four subunits of Torpedo electric organ acetylcholine receptor (AChR) for binding to intact AChR. 125I-α-bungarotoxin-labeled AChR was preincubated with a soluble mAb and the formed complex was incubated with a Sepharose-bound mAb. Care was taken to ensure that the competitive mAbs bound to only one subunit species.
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Tzartos, S.J., Kordossi, A.A. (1986). Acetylcholine Receptor Conformation Probed by Subunit-Specific Monoclonal Antibodies. In: Maelicke, A. (eds) Nicotinic Acetylcholine Receptor. NATO ASI Series, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71649-2_4
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