Abstract
As befits its importance to the relief of suffering in man, the writings on the history of local anesthesia are extensive, as those also were in relation to its predecessor, inhalation anesthesia. Strangely, those accounts appear largely in the American literature although the first clinical application of the anesthetic properties of cocaine took place in Vienna, in 1884. Full credit, as we shall see, is now given to Koller, the perpetrator. Although his contribution was not beset with the kind of controversy that surrounded the advent of inhalation anesthesia, it might have been that local politics, Koller’s aggressiveness and his religious adherence caused the event to be underemphasized abroad. Although regional anesthesia (a term reputedly coined by the American surgeon Harvey Cushing) was immediately applied clinically in America, the scientific basis and its multifold techniques were established in Germany around the turn of the century. In England, where there already existed a considerable degree of anesthetic professionalism, inhalation anesthesia continued to dominate despite decades of debate over the merits of chloroform, its mode of administration as well as adverse pharmacologic effects and toxicity. In that country to this day, regional anesthesia constitutes only a small share of practice while in America resurgence of interest in the method has occurred. Moreover, intravenous agents for induction and maintenance of general anesthesia now preoccupy practitioners both in England and on the continent.
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References
Abel JJ (1957), Investigator, teacher, prophet. 1857–1938. Williams and Wilkins, Baltimore
Abel JJ, Crawford AC (1897) On the blood pressure-raising constituent of the suprarenal capsule. Bull Johns Hopkins Hosp 8:151–156
Adrian ED (1932) The mechanism of nervous action. Oxford Press, London
Anrep, VK von (1880) Über die physiologische Wirkung des Cocain. Arch Ges Physiol 21:38–77
Becker HK (1963) Carl Koller and cocaine. Psychoanal Quart 32:309:373
Bieter RN (1936) Applied pharmacology of local anesthetics. Am J Surg 34:500–510
Boyes RN, Scott DB, Jebson PJ, Godman MJ, Julian DG (1971) Pharmacokinetics of li-docaine in man. Clin Pharmacol Ther 12:105:116
Braun H (1903) Über den Einfluß der Vitalität der Gewebe auf die örtlichen und allgemeinen Giftwirkungen lokaler anästhesierender Mittel und über die Bedeutung des Adrenalins für die Localanästhesie. Arch Klin Chir 69:541–591
Braun H (1905) Über einige neue örtliche Anästhetika (Stovain, Alypin, Novocain). Dtsch Med Wochenschr 2:1667–1671
Brodie BB, Lief, PA, Poet R (1948) The fate of procaine in man following its intravenous administration and methods for the estimation of procaine and diethyl-aminoethanol. J Pharmacol Exp Ther 94:359–366
Byck R (1974) Cocaine papers. Sigmund Freud. New American Library, New York
Caws P (1969) The structure of discovery. Scientific discovery is no less logical than deduction. Science 166:1375–1380
Cole KS (1982) Squid axon membrane. Impedance decrease to voltage clamp. Annu Rev Neurosci 3:303–323
Cole KS, Hodgkin AL (1939) Membrane and protoplasmic resistance in the squid giant axon. J Gen Physiol 22:671–678
Coming JL (1885) Spinal anaesthesia and local medication of the cord. NY Med J 42: 183–185
Curtis HJ, Cole KS (1938) Transverse impedance of the giant squid axon. J Gen Physiol 21:757–765
deJong RH, Bonin JD (1981) Benzodiazepines protect mice from local anesthetic convulsions and death. Anesth Analg 60:385–389
Duncan D, Jarvis WH (1943) Comparison of the actions on nerve fibers of certain anesthetic mixtures and substances in oil. Anesthesiology 4:465–474
Dunlop JG (1935) Fate of procaine in the dog. J Pharmacol Exp Ther 55:464–481
Eggleston C, Hatcher RA (1919) A further contribution to the pharmacology of the local anesthetics. J Pharmacol Exp Ther 13:433–487
Einhorn A (1899) On the chemistry of local anesthetics. MMW 46:1218–1220
Englesson S (1974) The influence of acid-base changes on central nervous system toxicity of local anaesthetic agents. I. Acta Anaesth Scand 18:79–87
Faulconer A, Keys TE (1965) Foundations of anesthesiology. Thomas, Springfield, IL
Fink BR (1980) History of local anesthesia. In: Cousins MJ, Bridenbaugh PO (eds) Neural blockade in clinical anesthesia and management of pain, chap 1. Lippincott, Philadelphia
Foldes FF, Davis DL, Plekss OJ (1956) Influence of halogen substitution on enzymatic hydrolysis. Anesthesiology 17:187–195
Foldes FF, Molloy R, McNail PG, Koukal LR (1960) Comparison of toxicity of intravenously given local anesthetic agents in man. JAMA 172:1493–1498
Freud S (1884) Über Coca. Zentralbl Ges Ther 2:289–314
Gasser HS, Erlanger JA (1929) The role of fiber size in the establishment of a nerve block by pressure or cocaine. Am J Physiol 88:581–591
Gay GR, Inaba DS, Rappolt TR Sr, Gushue GF Jr, Perkner JJ (1976) “An’ ho, ho, baby, take a whiff on me”: La Dama Blanca. Cocaine in current perspective. Anesth Analg 55:582–587
Greig ME, Holland WC, Lindvig PE (1950) The anesthetization of the rabbit’s cornea by non-surface anesthetics. Br J Pharmacol Chemother 5:461–464
Hatcher RA, Eggleston C (1916) A contribution to the pharmacology of novocaine. J Pharmacol Exp Ther 8:385–405
Hirschfelder AD, Bieter RN (1932) Local anesthetics. Physiol Rev 12:190–282
Hodgkin AL (1964) The conduction of the nervous impulse. Thomas, Springfield, IL
Hollunger H (1960) On the metabolism of lidocaine. Acta Pharmacol Toxicol 17:356–389
Kandel E (1982) The origins of modem neuroscience. Annu Rev Neurosci 5:299–303
Keys TE (1945) The history of surgical anesthesia. Schuman’s, New York
Kisch B, Koster H, Strauss E (1943) The procaine esterase. Exp Med Surg 1:51–64
Leser AJ (1940) Duration of local anesthesia in relation to concentrations of procaine and epinephrine. Anesthesiology 1:205–207
Marmont G (1949) Studies on the axon mambrane. J Cell Comp Physiol 34:351–382
Merton RK (1961) Singletons and multiples in scientific discovery. A chapter in the sociology of science. Proc Am Phil Soc 105:470–486
Mortimer WG (1974) History of coca, the “divine plant” of the Incas. AND/OR Press, San Francisco
Munson ES, Wagman IH (1972) Diazepam treatment of local anesthetic–induced seizures. Anesthesiology 37:523–528
Niemann A (1860) Sur Palcoloide de coca. J Pharmacol 34:474–475
Quincke H (1891) Die Lumbalpunction des Hydrozephalus. Berl Klin Wochenschr 28: 929–933
Ritchie IM, Greengard P (1966) On the mode of action of local anesthetics. Annu Rev Pharmacol 6:405–430
Tanaka K, Yamasaki M (1966) Blocking of cortical inhibitory synapses by intravenous lidocaine. Nature 209:207–208
Tatum AL, Atkinson AJ, Collins KH (1925) Acute cocaine poisoning, its prophylaxis and treatment in laboratory animals. J Pharmacol Exp Ther 26:325–335
Temkin O (1971) The historiography of ideas in medicine. Chapter I. In: Clarke E (ed) Modern methods in the history of medicine. Athlone, London
Thieulin J (1921) Urinary elimination of procaine. Chem Abstr 15:1167
Trendelenburg U (1958) The supersensitivity caused by cocaine. J Pharmacol Exp Ther 125:55–65
Williams LW (1909) The anatomy of the common squid, Loligo pealii Leseur, Leiden
Wöhler P (1860) Über eine organische Base in der Coca. Ann Chemie du Pharmac 114:213
Woods LA, McMahon FG, Seevers MH (1951) Distribution and metabolism of cocaine in the dog. J Pharmacol Exp Ther 101:200–204
Wynter WE (1891) Four cases of tuberculous meningitis in which paracentesis of the theca vertebralis was performed for the relief of fluid pressure. Lancet 1:981–982
Young JZ (1936) Structure of nerve fibres and synapses in some invertebrates. Cold Spring Harbor Symp Quant Biol 4:1–12
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Vandam, L.D. (1987). Some Aspects of the History of Local Anesthesia. In: Strichartz, G.R. (eds) Local Anesthetics. Handbook of Experimental Pharmacology, vol 81. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-71110-7_1
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DOI: https://doi.org/10.1007/978-3-642-71110-7_1
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