Abstract
In the previous chapter, we have shown how human satellite cRNA I, II, III, and IV hybridised with human and ape chromosomes mainly in regions of constitutive heterochromatin. In the great apes, as in man, it was also observed that many sites of hybridisation were the same for more than one satellite cRNA. In view of the lack of hybridisation of human cRNA II with chromosomes of Pan troglodytes, of human cRNA IV with chromosomes of Pongo, and, thirdly, of the different satellite cRNAs hybridised with interspecific homologue chromosomes, it was suggested that each sequence hybridising at each site was actually different from, and lacked close homology with, one another (Gosden et al., 1977). Based on this assumption it was also suggested that man and the species of great apes contained different kinds of highly repetitive DNA sequences arranged in tandem blocks at the same chromosomal site, a situation comparable to that observed in Drosophila melanogaster by Peacock et al. (1973).
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Seuánez, H.N. (1979). DNA Composition of Constitutive Heterochromatin in the Chromosome Complement of Man and the Great Apes. In: The Phylogeny of Human Chromosomes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67260-6_15
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DOI: https://doi.org/10.1007/978-3-642-67260-6_15
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