Summary
Abrupt arterial blood pressure elevation can give rise to multiple areas of protein extravasation in the brain. Vasodilation induced by papaverine or by hypercapnia aggravates this permeability disturbance. The water content in acute hypertension of 30 min duration was increased in hypercapnic but not in normo- or hypocapnic rats. The effect of hypercapnia per se on the blood-brain barrier is discussed in view of recent experimental findings.
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© 1976 Springer-Verlag Berlin · Heidelberg
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Johansson, B.B. (1976). Water Content of Rat Brain in Acute Arterial Hypertension. In: Pappius, H.M., Feindel, W. (eds) Dynamics of Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66524-0_6
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DOI: https://doi.org/10.1007/978-3-642-66524-0_6
Publisher Name: Springer, Berlin, Heidelberg
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