Abstract
Studies on the pathogenesis of normal pressure hydrocephalus (NPH) have been of necessity, limited to changes in the physical properties of the brains of patients whose cerebrospinal fluid (CSF) circulation is impaired, and whose symptoms reflect a progressive ventriculomegaly rather than an increased intraventricular pressure. The diagnosis of NPH is applied to patients with cerebral dysfunction, ataxia, enlarged cerebral ventricles, and normal spinal fluid pressure with no visible obstruction of the ventricular system. Considerable attention has been focused on devising means of distinguishing patients for whom the clinical picture can be reversed by shunting cerebrospinal fluid to another body cavity. The prognosis is good for patients identified as those who can benefit from the shunting procedure, in contrast to those with primary cerebral atrophy.
These studies were supported by USPHS Grant NS 06599.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
ADAMS, R.D., FISHER, C.M., HAKIM, S., OJEMANN, R.G., SWEET, W.H.: Symptomatic occult hydrocephalus with “normal” cerebrospinal fluid pressure. A treatable syndrome. New Engl. J. Med. 273, 117–126 (1965).
GESCHWIND, N.: The mechanism of normal pressure hydrocephalus. J. Neurol. Sci. 7, 481–493 (1968).
EPSTEIN, C.M.: The distribution of intracranial forces in acute and chronic hydrocephalus. J. Neurol. Sci. 21, 171–180 (1974).
RUBIN, R.C., HOCHWALD, G.M., LIWNICZ, B., TIELL, M., MIZUTANI, H., SHULMAN, K.: The effect of severe hydrocephalus on size and number of brain cells. Dev. Med. Child Neurol. 14, Suppl. 27, pp. 117–120 (1970).
KATZMAN, R., HUSSEY, F.: A simple constant infusion manometric test for measurement of CSF absorption. I. Rationale and method. Neurology (Minneap.) 20, 534–544 (1970).
HOCHWALD, G.M., LUX, W.E., JR., SAHAR, A., RANSOHOFF, J.: Experimental hydrocephalus: Changes in cerebrospinal fluid dynamics as a function of time. Arch. Neurol. 26, 120–129 (1972).
DIMATTIO, J., HOCHWALD, G.M., MALHAN, C.: The effects of the hydrocephalic process on cerebral blood flow in the cat. International Symposium on Cerebral Circulation and Metabolism, June 1973, Philadelphia, Penn., USA.
LORENZO, A.V., BRESNAN, M.J., BARLOW, C.F.: Cerebrospinal fluid absorption deficit in normal pressure hydrocephalus. Arch. Neurol. 30, 387–393 (1973).
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1975 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Hochwald, G.M. (1975). Co-chairman’s Introduction. In: Lundberg, N., Pontén, U., Brock, M. (eds) Intracranial Pressure II. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-66086-3_24
Download citation
DOI: https://doi.org/10.1007/978-3-642-66086-3_24
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-66088-7
Online ISBN: 978-3-642-66086-3
eBook Packages: Springer Book Archive