Abstract
Based on the experimental observations of the mechano-electrical transduction in hair cells, we formulate a model of the receptor potential utilizing a simple model circuit and ideas of stretch activation. The stereociliary displacement-response relation is developed based on the cilia crosslinking, thus incorporating notions of bidirectional sensitivity, asymmetry, saturation, and adaptation naturally into the model. We then give some simulation results involving periodic stimuli to the hair bundle as well as current stimuli to study latency behavior and other qualitative properties of the model.
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References
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© 1986 Springer-Verlag Berlin Heidelberg
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Bell, J., Holmes, M.H. (1986). A Model for Transduction in Hair Cells Involving Strain-Activated Conductance. In: Allen, J.B., Hall, J.L., Hubbard, A.E., Neely, S.T., Tubis, A. (eds) Peripheral Auditory Mechanisms. Lecture Notes in Biomathematics, vol 64. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-50038-1_47
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DOI: https://doi.org/10.1007/978-3-642-50038-1_47
Publisher Name: Springer, Berlin, Heidelberg
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