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Die Patientin mit Schilddrüsenerkrankung

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Perikonzeptionelle Frauenheilkunde

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Zusammenfassung

Bei der Beratung von Frauen mit Kinderwunsch können Schilddrüsenfragen auftreten, deren Lösung ganz unterschiedliche Behandlungszeiträume beansprucht:

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Literatur

  • Aydemir S, Ustundag Y, Bayraktaroglu T, Tekin IO, Peksoy I, Unal AU (2005) Fulminant hepatic failure associated with propylthoiuracil: a case report with treatment emphasis on the use of plasmapheresis. J Clin Apher 20: 235–238

    Article  PubMed  Google Scholar 

  • Azizi F, Hedayati M (2002) Thyroid function in breast-fed infants whose mothers take high doses of methimazole. J Endocrinol Invest 25: 493–496

    PubMed  CAS  Google Scholar 

  • Azizi F, Khoshniat M, Bahrainian M, Hedayati M (2000) Thyroid function and intellectual development of infants nursed by mothers taking methimazole. J Clin Endocrinol Metab 85: 3233–3238

    Article  PubMed  CAS  Google Scholar 

  • Bachrach LK, Burrow GN (1984) Aplasia cutis congenita and methimazole [letter]. Can Med Assoc J 130: 1264

    PubMed  CAS  Google Scholar 

  • Barbero P, Ricagni C, Mercado G, Bronberg R, Torrado M (2004) Choanal atresia associated with prenatal methimazole exposure: Three new patients. Am J Med Genet 129A: 83–86

    Article  PubMed  CAS  Google Scholar 

  • Barbero P, Valdez R, Rodriguez H, Tiscornia C, Mansilla E, Allons A, Coll S, Liascovich R (2008) Choanal atresia associated with maternal hyperthyroidism treated with methimazole: a case-control study. Am J Med Genet Part A 146A: 2390–2395

    Article  PubMed  Google Scholar 

  • Barwell J, Fox GF, Round J, Berg J (2002) Choanal atresia: The result of maternal thyrotoxicosis or fetal carbimazole? Am J Med Genet 111: 55–56

    Article  PubMed  Google Scholar 

  • Clementi M, Di Gianantonio E, Pelo E, Mammi I, Basile RT, Tenconi R (1999) Methimazole embryopathy: Delineation of the phenotype. Am J Med Genet 83: 43–46

    Article  PubMed  CAS  Google Scholar 

  • Di Gianantonio E, Schaefer C, Mastroiacovo PP, Cournot MP, Benedicenti F, Reuvers M, Occupati B, Robert E, Bellemin B, Addis A, Arnon J, Clementi M (2001) Adverse effects of prenatal methimazole exposure. Teratology 64: 262–266

    Article  PubMed  CAS  Google Scholar 

  • Diav-Citrin O, Ornoy A (2002) Teratogen update: antithyroid drugs – methimazole, carbimazole, and propylthiouracil. Teratology 65: 38–44

    Article  PubMed  CAS  Google Scholar 

  • Dutertre JP, Jonville AP, Moraine C, Autret E (1991) Aplasia cutis after exposure to carbimazole in utero [French]. J Gynecol Obstet Biol Reprod (Paris) 20: 575–576

    Google Scholar 

  • Farine D, Maidman J, Rubin S, Chao S (1988) Elevated alpha-fetoprotein in pregnancy complicated by aplasia cutis after exposure to methimazole. Obstet Gynecol 71: 996–997

    PubMed  CAS  Google Scholar 

  • Foulds N, Walpole I, Elmslie F, Mansour S (2005) Carbimazole embryopathy: an emerging phenotype. Am J Med Genet 132A: 130–135

    Article  PubMed  Google Scholar 

  • Greenberg F (1987) Choanal atresia and athelia: Methimazole teratogenicity or a new syndrome? Am J Med Genet 28: 931–934

    Article  PubMed  CAS  Google Scholar 

  • Hall BD (1997) Methimazole as a teratogenic etiology of choanal atresia/multiple congenital anomaly syndrome (abstract 557). Am J Hum Genet 61(s): A100

    Google Scholar 

  • Haddow JE, Palomaki GE, Allan WC, Williams JR, Knight GJ, Gagnon J, O’Heir CE, Mitchell ML, Hermos RJ, Waisbren SE, Faix JD, Klein RZ (1999) Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N Engl J Med 341: 549–555

    Article  PubMed  CAS  Google Scholar 

  • Iwayama H, Hosono H, Yamamoto H, Oshiro M, Ueda N (2007) Aplasia cutis congenita with skull defect in a monocygotic twin after exposure to methimazole in utero. Birth Defects Res A Clin Mol Teratol 79: 680–684

    Article  PubMed  CAS  Google Scholar 

  • Johnsson E, Larsson G, Ljunggren M (1997) Severe malformations in infant born to hyperthyroid woman on methimazole. Lancet 350: 1520

    Article  PubMed  CAS  Google Scholar 

  • Kalb RE, Grossman ME (1986) The association of aplasia cutis congenita with therapy of maternal thyroid disease. Pediatr Dermatol 3: 327–330

    Article  PubMed  CAS  Google Scholar 

  • Kampmann JP, Johansen K, Hansen JM, Helweg J (1980) Propylthiouracil in human milk. Revision of a dogma. Lancet 1:736–737

    Article  PubMed  CAS  Google Scholar 

  • Karlsson FA, Axelsson O, Melhus H (2002) Severe embryopathy and exposure to methimazole in early pregnancy. J Clin Endocrinol Metab 87(2): 946–951

    Article  Google Scholar 

  • Klasco RK (2005) REPROTOX database. Greenwood Village, CO: Thomson Micromedex

    Google Scholar 

  • Lamberg BA, Ikonen E, Osterlund K, Teramo K, Pekonen F, Peltola J, Valimaki M (1984) Antithyroid treatment of maternal hyperthyroidism during lactation. Clin Endocrinol (Oxf) 21: 81–87

    Google Scholar 

  • Laurberg P, Nygaard B, Glinoer D, Grussendorf M, Orgiazzi J (1998) Guidelines for TSH-receptor antibody measurements in pregnancy: results of an evidence-based symposium organized by the European Thyroid Association. Eur J Endocrinol 139: 584–586

    Google Scholar 

  • Mandel SJ, Brent GA, Larsen PR (1994) Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis. Thyroid 4: 129–133

    Google Scholar 

  • Mandel SJ, Cooper DS (2001) The use of antithyroid drugs in pregnancy and lactation. J Clin Endocrinol Metab 86: 2354–2359

    Article  PubMed  CAS  Google Scholar 

  • Martinez-Frias ML, Cereijo A, Rodriguez-Pinilla E, Urioste M (1992) Methimazole in animal feed and congenital aplasia cutis. Lancet 339: 742–743

    Article  PubMed  CAS  Google Scholar 

  • Milham S Jr (1985) Scalp defects in infants of mothers treated for hyperthyroidism with methimazole or carbimazole during pregnancy. Teratology 32: 321

    Article  PubMed  Google Scholar 

  • Milham S Jr, Elledge W (1972) Maternal methimazole and congenital defects in children [letter]. Teratology 5: 125–126

    Article  Google Scholar 

  • Momotani N, Yamashita R, Yoshimoto M, Noh J, Ishikawa N, Ito K (1989) Recovery from fetal hypothyroidism: evidence for the safety of breast-feeding while taking propylthiouracil. Clin Endocrinol (Oxf) 31: 591–595

    Google Scholar 

  • Mujtaba Q, Burrow GN (1975) Treatment of hyperthyroidism in pregnancy with propylthiouracil and methimazole. Obstet Gynecol 46: 282–286

    PubMed  CAS  Google Scholar 

  • Negro R, Formoso G, Mangieri T, Pezzarossa A, Dazzi D, Hasan H (2006) Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. J Clin Endocrinol Metab 91: 2587–2591

    Google Scholar 

  • Negro R, Greco G, Mangieri T, Pezzarossa A, Dazzi D, Hassan H (2007) The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol Metab 92: 1263–1268

    Google Scholar 

  • Ramirez A, Espinosa de los Monteros A, Parra A, De Leon B (1992) Oesophageal atresia and TOF in two infants born to hyperthyroid women receiving methimazole during pregnancy. Am J Med Genet 44: 200–202

    Article  PubMed  CAS  Google Scholar 

  • Russo MW, Galanko JA, Shrestha R et al. (2004) Liver transplantation for acute liver failure from drug induced liver injury in the United States. Liver Transpl (United States) 10 (8): 1018–1023

    Google Scholar 

  • Sargent KA, Stopfer JE, Mallozzi M, Khandelwal M, Quashie C, Schneider AS (1994) Apparent scalp-ear-nipple (Findlay) syndrome in a neonate exposed to methimazole in-utero [abstract]. Am J Hum Genet 55 (Suppl): A312

    Google Scholar 

  • Schlumberger M, De Vathaire F, Ceccarelli C, Delisle MJ, Francese C, Couette JE, Pinchera A, Parmentier C (1996) Exposure to radioactive iodine-131 for scintigraphy or therapy does not preclude pregnancy in thyroid cancer patients. J Nucl Med 37: 606–612

    Google Scholar 

  • Tanaka S, Yamashita Y, Koga Y, Hagisawa M, Hanatani K, Fujimoto S (1989) Three cases of neonatal congenital anomalies associated with maternal hyperthyroidism [abstract]. Teratology 40: 673–674

    Google Scholar 

  • Van Dijke CP, Heydendael RJ, De Kleine MJ (1987) Methimazole, carbimazole, and congenital skin defects. Ann Intern Med 106: 60–61

    Article  PubMed  CAS  Google Scholar 

  • Vogt T, Stolz W, Landthaler M (1995) Aplasia cutis congenita after exposure to methimazole: a causal relationship? Br J Dermatol 133: 994–996

    Article  PubMed  CAS  Google Scholar 

  • Wilson LC, Kerr BA, Wilkinson R, Fossard C, Donnai D (1998) Choanal atresia and hypothelia following methimazole exposure in utero: A second report. Am J Med Genet 75: 220–222

    Article  PubMed  CAS  Google Scholar 

  • WHO (World Health Organization), International Council for the Control of Iodine Deficiency Disorders (ICCIDD), United Nations Children’s Fund (UNICEF) (2007) Assessment of the iodine deficiency disorders and monitoring their elimination. Geneva: World Health Organization

    Google Scholar 

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Author information

Authors and Affiliations

  1. Universitätsklinikum Köln, Klinik und Poliklinik für Nuklearmedizin, Kerpenerstr. 62, 50937, Köln, Deutschland

    M. Dietlein

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  1. M. Dietlein
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Editors and Affiliations

  1. Grevenbroicher Endokrinologikum IVF-Zentrum, green-ivf, Grevenbroich, Germany

    Christian Gnoth

  2. Klinik u. Polikl. f. für Gyn. u. Gebh., Universitätsklinik Köln, Köln, Germany

    Peter Mallmann

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Dietlein, M. (2014). Die Patientin mit Schilddrüsenerkrankung. In: Gnoth, C., Mallmann, P. (eds) Perikonzeptionelle Frauenheilkunde. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-38023-5_11

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  • DOI: https://doi.org/10.1007/978-3-642-38023-5_11

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  • Print ISBN: 978-3-642-38022-8

  • Online ISBN: 978-3-642-38023-5

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