Abstract
The use of neuroprosthetic devices is currently hindered by a lack of safe and selective peripheral nerve interfaces (PNI). Research in the area typically characterizes new PNI designs in small simple nerve models using indirectly parameters of nerve recruitment.
The current work presents a new human size polyfascicular in vitro nerve model which enables direct assessment of fascicular recruitment characteristics of PNIs.
The model was used for characterizing the transverse intrafascicular multichannel electrode (TIME). Preliminary results demonstrate the feasibility of using the model and illustrate the high detail level which can be obtained with this model compared to typically used in vivo nerve models
This work was funded by the European Union in the 7th framework program under Grant CP-FP-INFSO-224012/TIME. The transverse intrafasicular multichannel electrodes (TIME) were provided by Tim Boretius and Thomas Stieglitz, Department of Microsystems Engineering, University of Freiburg, Germany.
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Harreby, K.R., Sevcencu, C., Jensen, W. (2013). In vitro Large Polyfascicular Nerve Model for Assessment of Fascicular Recruitment Characteristics of Peripheral Nerve Interfaces. In: Pons, J., Torricelli, D., Pajaro, M. (eds) Converging Clinical and Engineering Research on Neurorehabilitation. Biosystems & Biorobotics, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34546-3_65
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DOI: https://doi.org/10.1007/978-3-642-34546-3_65
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