Abstract
Modified methods aimed for future studies of chemoreflex control of breathing during long space missions are presented. A study of the control in sitting and head-down supine subjects was performed by these methods. Tidal volume and ventilatory hypercapnic responses were analyzed in PETCO2 range between 45 mmHg and 65 mmHg. Progressive hypercapnic – hypoxic rebreathing revealed posture changes in chemoreflex control, so it is reasonable to use this method in space studies as well as the methods of hyperoxic rebreathing and of isocapnic rebreathing. Chemoreflex control of tidal volume response, i.e. VTR, has a greater sensitivity to posture than ventilation response, i.e. VR, so it is recommended to include tidal volume in the parameters of study in space flights.
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© 2013 Springer-Verlag Berlin Heidelberg
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Ermolaev, E.S., Dyachenko, A.I., Shulagin, Y.A., Goncharov, A.O., Demin, A.V. (2013). Effect of head-down human body position on chemoreflex control of breathing. In: Long, M. (eds) World Congress on Medical Physics and Biomedical Engineering May 26-31, 2012, Beijing, China. IFMBE Proceedings, vol 39. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-29305-4_543
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DOI: https://doi.org/10.1007/978-3-642-29305-4_543
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-29304-7
Online ISBN: 978-3-642-29305-4
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