2-Pyridone formation from the condensation of cyanoacetic ester with diketone in the presence of ammonia.
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(a) Guareschi, I. Mem. R. Accad. Sci. Torino 1896, II, 7, 11, 25. (b) Baron, H.; Renfry, F. G. P.; Thorpe, J. F. J. Chem. Soc. 1904, 85, 1726–1961. Jocelyn F. Thorpe spent two years in Germany where he worked in the laboratory of a dyestuff manufacturer before taking a post as a lecturer at Manchester. Thorpe later became FRS (Fellow of the Royal Society) and professor of organic chemistry at Imperial College.
Vogel, A. I. J. Chem. Soc. 1934, 1758–1765.
McElvain, S. M.; Lyle, R. E. Jr. J. Am. Chem. Soc. 1950, 72, 384–389.
Brunskill, J. S. A. J. Chem. Soc. (C) 1968, 960–966.
Brunskill, J. S. A. J. Chem. Soc., Perkin Trans. 1 1972, 2946–2950.
Holder, R. W.; Daub, J. P.; Baker, W. E.; Gilbert, R. H. III; Graf, N. A. J. Org. Chem. 1982, 47, 1445–1451.
Krstic, V.; Misic-Vukovic, M.; Radojkovic-Velickovic, M. J. Chem. Res. (S) 1991, 82.
Galatsis, P. Guareschi–Thorpe Pyridine Synthesis. In Name Reactions in Heterocyclic Chemistry; Li, J. J., Corey, E. J., Eds.; Wiley & Sons: Hoboken, NJ, 2005, pp 307–308. (Review).
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Li, J.J. (2009). Guareschi–Thorpe condensation. In: Name Reactions. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01053-8_116
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DOI: https://doi.org/10.1007/978-3-642-01053-8_116
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