Abstract
In this paper, we propose a new fabrication method of pH-responsive microfluidic valves and suggest the feasibility as a microminiature systems without peripheral devices. Conventionally, in-situ photopolymerization method has been employed to build the micro functional structure inside microfluidic channel. Here, we suggest a new method allowing the mass production of stimuli-responsive microsystem through the use of pre-made microstructure as actuating element like assembly of commercial products in the factory. We have massively fabricated pH-responsive microspheres that act as actuating component through the use of PDMS-based microfluidic apparatus and ‘on the fly’ photopolymerization method. By the incorporation of this microsphere into the microvalve during the fabrication process, we have produced the pH-responsive microfluidic valve in a simple way. The operation and the function of the fabricated microvalve were evaluated through the diverse experiments. The microvalve was successfully fabricated, and functioned well according to the pH change.
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© 2007 International Federation for Medical and Biological Engineering
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Park, J.Y., Kim, D.J., Kim, S.R., Baek, J.Y., Sun, K., Lee, S.H. (2007). Fabrication and Evaluation of Polymeric Microvalve using the pH-Responsive Hydrogel Microsphere. In: Magjarevic, R., Nagel, J.H. (eds) World Congress on Medical Physics and Biomedical Engineering 2006. IFMBE Proceedings, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36841-0_82
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DOI: https://doi.org/10.1007/978-3-540-36841-0_82
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36839-7
Online ISBN: 978-3-540-36841-0
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