Abstract
The talk will describe the general issues in Bayesian approaches to haplotype reconstruction, including the distinction between choice of prior distribution, and the computational methods used to approximate posterior distributions. We describe recent improvements to the software PHASE, including handling missing data and improved computational methods, and compare its behaviour to some other published methods.
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© 2004 Springer-Verlag Berlin Heidelberg
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Donnelly, P. (2004). Bayesian Methods for Statistical Reconstruction of Haplotypes. In: Istrail, S., Waterman, M., Clark, A. (eds) Computational Methods for SNPs and Haplotype Inference. RSNPsH 2002. Lecture Notes in Computer Science(), vol 2983. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-24719-7_15
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DOI: https://doi.org/10.1007/978-3-540-24719-7_15
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-21249-2
Online ISBN: 978-3-540-24719-7
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