Abstract
Lymphatic vessels play a critical role in the lung because they remove excess fluid and protein from the lung tissue. Fluid and protein continuously filter from the lung microvessels, and if it were not for the lymphaic vessels, this filtrate would accumulate within the lung [20, 39]. Investigators may learn much about the lymphatic system by studying the flow characteristics of cannulated lymphatic vessels. In addition, cannulated lympatics are a powerful tool in studies of lung microvascular permeability [36]. Most estimates of microvascular permeability require some measure of 1) microvascular filtration rate and 2) filtrate protein concentration. Because the lymphatics drain microvascular filtrate from the lung tissue, investigators may estimate filtration rate from the lymph flow rate and filtrate protein concentration may be estimated from lymph protein concentration.
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Drake, R.E., Gabel, J.C. (1998). Lymphatics. In: Uhlig, S., Taylor, A.E. (eds) Methods in Pulmonary Research. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-8855-4_11
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DOI: https://doi.org/10.1007/978-3-0348-8855-4_11
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