Abstract
Studies were made of polyamine and Mg++ effects on rat liver mitochondrial α ketoglutarate oxidase (αKGO) and succinoxidase (SO). High spermidine levels suppress S3 and S4 of αKGO at 0.6–1.17 mM Mg++: some combinations of it and Mg++ increase the respiratory control ratio (RCR). Spermine suppresses S4 of αKGO and increases the RCR but suppresses the RCR of SO at high levels. In heat-acclimated (HA) animals in which we have studied only spermine effects on αKGO, RCRs of HA rats are greatly increased compared to those of controls.
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© 1978 Springer Basel AG
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Chaffee, R.R.J., Arine, R.M.R., Rene, H., Walker, C.D. (1978). Polyamine and Magnesium Effects on Mitochondrial Respiration in Control and Heat-Acclimated Rats. In: Girardier, L., Seydoux, J. (eds) Effectors of Thermogenesis. Experientia Supplementum, vol 32. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-5559-4_10
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DOI: https://doi.org/10.1007/978-3-0348-5559-4_10
Publisher Name: Birkhäuser, Basel
Print ISBN: 978-3-0348-5561-7
Online ISBN: 978-3-0348-5559-4
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