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Automated Depression Diagnosis in MDD (Major Depressive Disorder) Patients Using EEG Signal

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Innovations in Bio-Inspired Computing and Applications (IBICA 2022)

Part of the book series: Lecture Notes in Networks and Systems ((LNNS,volume 649))

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Abstract

The detection of major depression is very critical process. The identification and treatment of depression at right time is very essential for well-being of person along with family and society. The acquisition of signal from patient is complex and time-consuming process. So, Multi-modal Open Dataset for Mental-disorder Analysis (MODMA) is considered to accomplish present research work. Different modalities are available for identification of mental stress but here in this work, Electroencephalography (EEG) technique is chosen due to its painless and low-cost features. All the relevant 10 features (linear and non-linear features) are calculated from the dataset of 10 subjects (5 MDD and 5 Healthy Control (HC)) using EEG LAB toolbox in MATLAB R2020b software. The array of matrix of various features is formed for all subjects (5 MDD and 5 HC). All 128-channel EEG data features calculated in more effective way. The classification process is accomplished using 5 Classifiers named Linear SVM (Support Vector Machine), Fine Tree, LR (Logistic Regression), Kernel Naïve Bayes and Fine KNN (K-Nearest Neighbor) for better accuracy. The highest average correct classification rate for Fine Tree classifier for 5 features and 10 features is found to be 99.52% and 99.68%, respectively. These results are compared with other classifiers to reach final conclusion of finding best modality to differentiate MDD patient from healthy one. In this way, we find out best classifier for detection of depression using MODMA dataset of 128-channel EEG signal.

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References

  1. Chen, Z., et al.: High-field magnetic resonance imaging of suicidality inpatients with major depressive disorder. Amer. J. Psychiatry 167(11), 1381–1390 (2010)

    Article  Google Scholar 

  2. Santini, Z.I., Koyanagi, A., Tyrovolas, S., Mason, C., Haro, J.M.: The association between social relationships and depression: a systematic review. Journal of Affective Disorders, vol. 175, pp. 53–65( 2015)

    Google Scholar 

  3. Brundtland, G.H.: From the World Health Organization. Mental health: new understanding, new hope. J. Am. Med. Assoc. 286(19), 2391 (2001)

    Google Scholar 

  4. Dutta, A., Mckie, S., Deakin, J.F.W.: Resting state networks in major depressive disorder. Psychiatry Res. 224(3), 139–151 (2014)

    Article  Google Scholar 

  5. Kaiser, R.H., Andrews-Hanna, J.R., Wager, T.D., Pizzagalli, D.A.: Large-scale network dysfunction in major depressive disorder: A meta-analysis of resting-state functional connectivity. JAMA Psychiat. 72(6), 603 (2015)

    Article  Google Scholar 

  6. Pizzagalli, D.A.: Frontocingulate dysfunction in depression: toward biomarkers of treatment response. Neuropsychopharmacology 36(1), 183–206 (2011)

    Article  Google Scholar 

  7. Kumar, J.S., Bhuvaneswari, P.: Analysis of Electroencephalography (EEG) signals and its categorization-A study. International conference on Modeling, Optimization and Computing (ICMOC 2012) Procedia engineering, ELSEVIER 38, 2525–2536 (2012)

    Google Scholar 

  8. Manea, L., Gilbody, S., McMillan, D.: A diagnostic meta-analysis of the Patient Health Questionnaire-9 (PHQ-9algorithm scoring method as a screen for depression. Gen. Hosp. Psychiatry 37(1), 67–75 (2015)

    Article  Google Scholar 

  9. Georgieva, S., Tomas, J.M., Navarro-P´erez, J.J.: Systematic review and critical appraisal of Childhood Trauma Questionnaire — Short Form (CTQ-SF). Child Abuse & Neglect 120, 105223 (2021)

    Google Scholar 

  10. Horowitz, M., Wilner, N., Alvarez, W.: Impact of Event Scale: A Measure of Subjective Stress. Psychosom. Med. 41(3), 209–218 (1979)

    Article  Google Scholar 

  11. Cheng, Y., Liu, C., Mao, C., Qian, J., Liu, K., Ke, G.: Social support plays a role in depression in Parkinson’s disease: a cross-section study in a Chinese cohort. Parkinsonism Relat. Disord. 14, 43–45 (2008)

    Article  Google Scholar 

  12. Plummer, F., Manea, L., Trepel, D., McMillan, D.: Screening for anxiety disorders with the GAD-7 and GAD-2: a systematic review and diagnostic metaanalysis. Gen. Hosp. Psychiatry 39, 24–31 (2016)

    Article  Google Scholar 

  13. Mollayeva, T., Thurairajah, P., Burton, K., Mollayeva, S., Shapiro, C.M., Colantonio, A.: The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep Med. Rev. 25, 52–73 (2015)

    Article  Google Scholar 

  14. Hamilton, M.: A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 23(1), 56–62 (1960)

    Article  Google Scholar 

  15. Cai, H., et al.: A Multi-modal Open Dataset for Mental-Disorder Analysis 9, 178 (2022)

    Google Scholar 

  16. Liu, X., Zhang, Y., Bao, F., Shao, K., Sun, Z., Zhang, C.: Kernel-blending connection approximated by a neural network for image classification. Comput. Visual Media 6(4), 467–476 (2020). https://doi.org/10.1007/s41095-020-0181-9

    Article  Google Scholar 

  17. Lamba, R., Gulati, T., Alharbi, H., Jain, A.: A hybrid system for Parkinson’s disease diagnosis using machine learning techniques. Int.J. Speech Technol, 1-11 (2021)

    Google Scholar 

  18. Sani, M., Norhazman, H., Omar, H., Zaini, N., Ghani, S.A.: Support Vector Machine for classification of stress subjects using EEG signals, in: Proceedings of the IEEE Conference on Systems, Process and Control (ICSPC 2014), IEEE (2014)

    Google Scholar 

  19. Safavian, S.R., Landgrebe, D.: A survey of decision wee classifier methodology. IEEE Trans. Syst. Man Cybern. 21(3), 660–674 (1991)

    Article  Google Scholar 

  20. Navada, A., Ansari, A., Patil, S., Sonkamble, B.: Overview of use of decision tree algorithms in machine learning. IEEE Control Syst Graduate Res Colloquium, 37–42 (2011)

    Google Scholar 

  21. Bishop, C.M.: Pattern Recognition and Machine Learning (Information Science and Statistics). Springer-Verlag, New York, Inc., Secaucus, NJ, USA (2006)

    Google Scholar 

  22. Flach, P.A., Lachiche, N. :Naive Bayesian Classification of Structured Data. Machine Learning, Kluwer Academic Publishers, Boston, pp- 1–37 (2004)

    Google Scholar 

  23. Li, B., Yu, S., Lu, Q.: An improved K- nearest neighbor algorithm for text categorization. Proceedings of the 20th International conference on computer processing of Oriental Languages, Sheyang, China (2003)

    Google Scholar 

  24. Alpaydin, E.: Introduction to Machine Learning. 4th ed. MIT Press, Cambridge (2020)

    Google Scholar 

  25. Movahed, R.A., Jahromi, G.P., Shahyad, S., Meftahi, G.H.: A major depressive disorder classification framework based on EEG signals using statistical, spectral, wavelet, functional connectivity, and nonlinear analysis. J. Neurosci. Methods 358, 109209 (2021)

    Article  Google Scholar 

  26. Peng, H., et al.: Multivariate Pattern analysis of EEG-based functional connectivity: a study on the identification of depression. IEEE Access. 7, 92630–92641 (2019)

    Article  Google Scholar 

  27. Sun, S., Li, J., Chen, H., Gong, T., Li, X., Hu, B.: A study of resting-state EEG biomarkers for depression recognition (2020)

    Google Scholar 

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Correspondence to Sweety Singh .

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Singh, S., Sheoran, P., Duhan, M. (2023). Automated Depression Diagnosis in MDD (Major Depressive Disorder) Patients Using EEG Signal. In: Abraham, A., Bajaj, A., Gandhi, N., Madureira, A.M., Kahraman, C. (eds) Innovations in Bio-Inspired Computing and Applications. IBICA 2022. Lecture Notes in Networks and Systems, vol 649. Springer, Cham. https://doi.org/10.1007/978-3-031-27499-2_21

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