Abstract
This small tree of the ANNONACEAE family is 5 to 7 meters in height. The leaves are oblong-obovate to oblong, 2 to 15 cm long, pointed at both ends, smooth, shiny, usually with petioles 5 cm long. Flowers are large and solitary, yellowish or greenish-yellow in color. Three outer petals are broadly ovate with heart-shaped base, inner 3 also large, elliptical and rounded. The fruit ovoid, 18 cm long or more, is covered with scattered spine-like structures. The pulp is soft white, and rather fibrous and fleshy, with an agreeable sour flavor.
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References
Spencer, C. F., F. R. Koniuszy, E. F. Rogers, et al. Survey of plants for antimalarial activity. Lloydia 1947; 10: 145–174.
Haddock, R. L. Some Medicinal Plants of Guam Including English and Guamanian Common Names. Report Regional Tech Mtg Med Plants, Papeete, Tahiti, Nov, 1973, South Pacific Commissioner, Noumea, New Claedonia 1974; 79.
Feng, P. C., L. J. Haynes, K. E. Magnus, J. R. Plimmer and H. S. A. Sherrat. Pharmacological screening of some West Indian medicinal plants. J Pharm Pharmacol 1962; 14: 556–561.
Santos, G. A., J. R. Librea, A. C. Santos. The alkaloids of Annona muricata. Philippine J Sci 1967; 96: 399.
Callan, T. and F. Tutin. Chemical examination of the leaves of Annona muricata. Pharm J 1914; 87: 743.
Cutolo, A. The composition of the fruit Annona cherimolia. Staz Sper Agr ital 1915; 48: 889.
Hermano, A. J. and G. Sepulveda Jr. The vitamin content of Philippine foods. II. Vitamin C in various fruits and vegetables. Philippine J Sci 1934; 53:379.
Meyer, T. M. The alkaloids of Annona muricata. Ing Ned Indie 1941; 8(6): 64.
Asenjo, C. F. and J.A. Goyco. Puerto Rican fatty oils. II. The characteristics and composition of guanabana seed oil. J Amer Chem Soc 1943; 65: 208.
Ventura, M. M. and I. H. Lima. Ornithine cycle amino acids and other free amino acids in fruits of Annona squamosa and A. muricata. Phyton (Buenos Aires) 1961; 17:39.
Willaman, J. J. and B. G. Schubert. Alkaloid bearing plants and their contained alkaloids. ARS, USDA, Tech Bull 1234, Supt Documents, Govt Print Off, Washington DC 1961.
Morton, J. F. A survey of medicinal plants of Curacao. Econ Bot 1968; 22: 87.
Watt, J. M. and M. G. Breyer-Brandwijk. The Medicinal and Poisonous Plants of Southern and Eastern Africa. 2nd Ed, E. S. Livingstone, Ltd., London, 1962.
Griffiths, L. A. On the distribution of gentisic acid in green plants. J Exp Biol 1959; 10: 437.
Ur-Rahman, A., H. M. Said and V. U. Ahmad. Pakistan Encyclopaedia Planta Medica, Vol. I. Hamdard Foundation Press, Karachi, Pakistan 1986; 373pp.
Reiser, M. J., J. F. Kozlowski, K. V. Wood and J. L. Mc Laughlin. Muricatacin: A simple biologically active acetogenin derivative from the seeds of Annona muricata (Annonaceae). Tetrahedron Lett 1991; 32(9): 1137–1140.
Myint, S. H., D. Cortes, A. Laurens, R. Hocquemiller, M. Lebceuf, A. Cave, J. Cottc and A. M. Quero. Solamin, a cytotoxic mono-tetrahydrofuranic gamma-lactone acetogenin from Annona muricata seeds. Phytochemistry 1991; 30 (10): 3335–3338.
Cortes, D., S. H. Myint, A. Laurens, R. Hocquemiller, M. Leboeuf and A. Cave. Corossolone and corossoline, two new monotetrahydrofuran gamma lactones. Can J Chem 1991; 69(1): 8–11.
Jossang, A., B. Dubaele, A. Cave, M. H. Bartoli and H. Beriel. Cytotoxic gamma lactone monotetrahydrofuran annomontacin: A new acetogen from Annona muricata. J Nat Prod 1991; 54(4): 967–971.
Gromek, D., B. Figadere, R. Hocoquemiller and A. Cave. Corepoxylone, a possible precursor of mono-tetrahydrofuran gamma-lactone acetogenins: Biometrie synthesis of corossolone. Tetrahedron 1993; 49 (24): 5247–5252.
Hisham, A., U. Sreekala, L. Pieters, T. De Bruyne, H. Vanden Heuvel and M. Claeys. Tetrahedron 1993; 49(31): 6913–6920.
Rieser, M.J., X. P. Fang, J. E. Anderson, L. R. Miesbauer, D. L. Smith and J. L. Mc Laughlin. Muricatetrocins A and B and gigantetrocin B: Three new citotoxic monotetrahydrofuran-ring acetogenins from Annona muricata I. Helv Chim Acta 1993; 76(7): 2433–2444.
Roblot, F., T. Laugel, M. Lebqueue, A. Cave and O. Laprevote. Two acetogenins from Annona muricata seeds. Phytochemistry 1993; 34(1): 281–285.
Yang, R. Z., S. J. Wu, R. S. Su and G. W. Qin. Annonaceous acetogenins from Annona muricata. Yun-Nan Chih Wu Yen Chiu 1994; 16(2): 187–190.
Yang, R. Z., S. J. Wu, R. S. Su, D. J. Fan and G. W. Qin. Annonaceous acetogenins from Annona muricata. Chih Wu Hsueh Pao 1994; 36(10); 805–808.
Wu, F. E., Z. M. Gu, L. Zeng, G. X. Zhao, Y. Zhang and]. L. Mc Laughlin. Two new cytotoxic monotetra-hydrofuran annonaceous acetogenins, annomuricins A and B, from the leaves of Annona muricata. J Nat Prod 1995; 58(6): 830–836.
Wu, F. E., L. Zeng, Z. M. Gu, G. X. Zhao, Y. Zhang, J. T. Schwedler, J. L. Mc Laughlin and S. Sastrodihardjo. New bioactive monotetrahydrofuran annonaceous acetogenins, anno-muricin C and muricatocin C., from the leaves of Annona muricata. J Nat Prod 1995; 58(6): 909–915.
Wu, F. E., L. Zeng, Z. M. Gu, G. X. Zhao, Y. Zhang, J. T. Schwedler, J. L. Mc Laughlin and S. Sastrodihardjo. Muricatocins A and B, two new bioactive monotetrahydrofuran annonaceous acetogenins from the leaves of Annona muricata. J Nat Prod 1995; 58(6): 902–908.
Misas, C. A. J., N. M. R. Hernandez and A. M. L. Abraham. Contribution to the biological evaluation of Cuban plants. IV. Rev Cub Med Trop 1979; 31(1): 29–35.
Rieser, M. J., X. P. Fang, J. K. Rupprecht, Y. H. Hui, D. L. Smith and J. L. Mc Laughlin. Bioactive single-ring acetogenins from seeds extracts of Annona muricata. Planta Med 1993; 59(1): 91–92.
Sundarrao, K., I. Burrows, M. Kuduk, Y. D. Yi, M. H. Chung, N. J. Suh, I. M. Chang. Preliminary screening of antibacterial and antitumor activities of Papua, New Guinean native medicinal plants. Int J Pharmacog 1993; 31(1): 3–6.
Antoun, M. D., L. Gerena and W. K. Milhous. Screening of the flora of Puerto Rico for potential antimalarial bioactives. Int J Pharmacog 1993; 31(4): 255–258.
Heinrich, M., M. Kuhnt, C. W. Wright, H. Rimpler, J. D. Phillipson, A. Schandelmaier and D. C. Warhurst. Parasitological and microbiological evaluation of Mixe Indian medicinal plants (Mexico). J Ethnopharmacol 1992; 36(1): 81–85.
Holdsworth, D. K. Traditional medicinal plants of Rarotonga, Cook Islands, Part 1. Int J Crude Drug Res1990; 28(3): 209–218.
Gromek, D., R. Hocquemiller and A. Cave. Qualitative and quantitative evaluation of annonaceous acetogenins by high performance liquid chromatography. Phytochem Anal 1994: 5(3): 133–140.
Yang, R. Z. and S. J. Wu. Annonaceous acetogenins from Annona muricata (111). Yunnan Zhiwu Yanjiu 1994; 16(3): 309–310.
Joyeux, M., F. Mortier and J. Fleurentin. Screening of antiradical, antilipoperoxidant and hepatoprotec-tive effects of nine plant extracts used in Caribbean folk medicine. Phytother Res 1995; 9(3): 228–230.
Di Stasi, L. C., M. Costa, L.J. Mendacolli, M. Kirizawa, C. Gomes and G. Trolin. Screening in mice of some medicinal plants used for analgesic purposes in the state of Sao Paulo. J Ethnopharmacol 1988; 24 (2/3): 205–211.
Evans, D. A. and R. K. Raj. Extracts of Indian plants as mosquito larvicides. Indian J Med Res1988; 88(1): 38–41.
Greassor, M., A. Y. Kedjagni, K. Koumaglo, C. DeSouza, K. Agbo, K. Aklikokou and K. A. Amegbo. In vitro antimalarial activity of six medicinal plants. Phytother Res1990; 4(3): 115–117.
Ohsawa, K., S. Kato, H. Honda and I. Yamamoto. Pesticidal substances in tropical plants. Insecticidal substances from annonaceae seeds. Nogaku Shuho (Tokyo Nagyo Daigaku) 1990; 34(4): 253–258.
Caceres, A., B. R. Lopez, M. A. Giron and H. Logemann. Plants used in Guatemala for the treatment of dermatophytic infections. I. Screening for anti-mycotic activity of 44 plant extracts. J Ethnopharmacol 1991; 31(3): 263–276.
Bories, C., P. Loiseau, S. H. Myint, R. Hocquemiller, P. Gayral, A. Cave and A. Laurens. Antiparasitic activity of Annona muricata and Annona cherimoiai seeds. Planta Med 1991; 57(5): 434–436.
Carbajal, D., A. Casaco, L. Arruzazabala, R. Gonzalez and V. Fuentes. Pharmacological screening of plant decoctions commonly used in Cuban folk medicine. J Ethnopharma’ col 1991; 33(1/2): 21–24.
Ayensu, E. S. Medicinal plants of the West Indies. Unpublished Manuscript 1978; 110 pp.
Gupta, M. P., T. D. Arias, M. Correa and S. S. Lamba. Ethnopharma-cognostic observations on Panamanian medicinal plants. Part 1. Q J Crude Drug Res 1979; 17(3/4): 115–130.
Izzo, R. Composition of Annona muricata seed oil. Riv Soc Ital Sci Aliment 1979; 8: 241–244.
Leboeuf, M., C. Leguet, A. Cave, J. F. Desconclois and P. Forgascs. Anomurine and anomuricine, two new isoquinoline alkaloids from Annona muricata. (Abstract). Planta Med 1980; 39: 204–205.
Leboeul, M., C. Legueut, A. Cave, J. F. Desconclois, P. Forgacs and H. Jacquemin. Alkaloids of annonaceae. XXXIX. Alkaloids of Annona muricata. Planta Med 1981; 42: 37–44.
Medina, F. R. and R. Woodbury. Ter-restrial plants molluscicidal to Lymnaeid hosts of Fasciliasis hepatica in Puerto Rico. J Agr Univ Puerto Rico 1979; 63: 366–376.
Morton, J. F. Caribbean and Latin American folk medicine and its influence in the United States. Q J Crude Drug Res1980; 18(2): 57–75.
Iwu, M. M. and B. N. Anyanwu. Phytotherapeutic profile of Nigerian herbs. 1. Anti-inflammatory and anti-arthritic agents. J Ethnopharmacol 1982; 6(3): 263–274.
Adesina, S. K. Studies on some plants used as anticonvulsants in Amerindian and African traditional medicine. Fitoterapia 1982; 53: 147–162.
Lopez Abraham, A. N., N. M. Rojas Hernandez and C. A. Jimenez Misas. Potential antineoplastic activity of Cuban plants. IV. Rev Cubana Farm 1981; 15(1): 71–77.
Escarraman Mata, S., M. Del Refugio, F. Juarez and A. Gonzalez Perez. Determination of seven flavor components of custard apple by gas chroma-tography. Tecnol Aliment (Mexico City) 1982; 17(6): 3,4,6,7.
Weniger, B., M. Rouzier, R. Daguilh, D. Henrys, J. H. Henrys and R. Anthon. Popular medicine of the Central Plateau of Haiti. 2. Ethnopharma-cological inventory. J Ethnopharmacol 1986; 17(1): 13–30.
Vietmeyer, N. D. Lesser-known plants of potential use in agriculture and forestry. Science 1986; 232(4756): 1379–1384.
Tattersfield, F. and C. Potter. The in-secticidal properties of certain species of annona and an Indian strain of Mundulea sericea (Suppl). Ann Appl Biol 1940; 27: 262–273.
Oakes, A. J. and M. P. Morris. The West Indian weedwoman of the United States Virgin Islands. Bull Hist Med 1958; 32: 164.
Hodge, W. H. and D. Taylor. The ethnobotany of the island Caribes of Dominica. WEBBIA 1956; 12: 513–644.
Asprey, G. F. and P. Thornton. Medicinal plants of Jamaica. III. West Indian Med 1955; J4: 69–82.
Callan, T. and F. Tutin. Chemical examination of the leaves of Annona muricata. Pharm J 1912; 87: 743–745.
Jelliffe, D. B., G. Bras and K. L. Stuart. The clinical picture of veno-occlusive disease of the liver in Jamaican children. Ann Trop Med Parasitol 1954; 48: 386–396.
ANON. Unpublished data, National Cancer Institute. National Cancer Inst. Central Files 1976.
Rieser, M. J., M. Z. Gu, X. P. Fang, L. Zeng, K. V. Wood and J. L. McLaughlin. Five novel mono-tet-rahydrofuran ring acetogenins from the seeds of Annona muricata. J NatProd 1996; 59(2): 100–108.
Zeng, L, F. E. Wu, N. H. Oberlies, J. H. McLaughlin and S. Sastrodihadjo. Five new monotetrahydrofuran ring acetogenins from the leaves of Annona muricata. J Nat Prod 1996; 59(11): 1035–1042.
Hasrat, J. A., T. De Bruyne, J. P. De Backer, G. Vauquelin and A. J. Vlietinck. Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-Htergic 5-HT1A receptor agonist in rats: unexploited antidepressive (lead) products. J Pharm Pharmacol 1997; 49(11): 1145–1149.
Kim, G. S., L. Zeng, F. Mali, L. L. Rogers, F. E. Wu, J. L. McLaughlin and S. Sastrodihardjo. Two new mono-tet-rahydrofuran ring acetogenins, annomuricin E and muricapentocin, from the leaves of Annona muricata, J Nat Prod 1998; 61(4): 432–436.
Gleye, C., P. Duret, A. Laurens, R. Hocquemiller and A. Cave. Cis monotetrahydrofuran acetogenins from the roots of Annona muricata I. J Nat Prod 1998; 61(5): 576–579.
Padma, P., N. P. Pramod, S. P. Thyagarajan and R. L. Khosa. Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus. J Ethnopharmacol 1998; 61(1): 81–83.
Kim, G. S., L. Zeng, F. Mali, L. L. Rogers, F. E. Wu, S. Sastrodihardjo and J. L. McLaughlin. Muricoreacin and murihexocin C., monotetrahydrofuran acetogenins, from the leaves of Annona muricata. Phytochemistry 1998; 49(2): 565–571.
Betancur-Galvis, L., J. Saez, H. Granados, A. Salazar and J. Ossa. Antitumor and antiviral activity of Colombian medicinal plant extracts. Mem Inst Oswaldo Cruz 1999; 94(4): 531–535.
Dos Santos, A. F. and A. E. Sant’Ana. The molluscicidal activity of plants used in Brazilian fold medicine. Phytomedicine 2000; 6(6): 431–438.
Jarmaillo, M. C., G. J. Arango, M. C. Gonzlalez, S. M. Robeldo and I. D. Velez. Cytotoxicity and antileishmanial activity of Annona muricata pericarp. Fitoterapia 2000; 71(2): 183–186.
Gleye, C., S. Raynaud, C. Fourneau, A. Laurens, O. Laprevote, L. Serani, A. Fournet and R. Hocquemiller. Cohibins C and D, two important metabolites in the biogenesis of acetogenins from Annona muricata and Anona nutans.J Nat Prod 2000; 63(9): 1192–1196.
Dos Santos, A. F. and A. E. Sant’Ana. Molluscicidal properties of some species of Annona. Phytomedicine 2001; 8(2): 115–120.
Chang, F. R. and Y. C. Wu. Novel cytotoxic annonaceous acetogenins from Annona muricata. J Nat Prod 2001; 64(7): 925–931.
Gleye, C., B. Akendengue, A. Laurens and R. Hocquemiller. Coronin from roots of Annona muricata, a putative intermediate in acetogenin biosynthesis (I). Planta Med 2001; 67(6): 570–572.
Yu, J. G., H. Q. Gui, X. Z. Luo, L. Sun, P. Zhu and Z. L. Yu. Studies on the chemical constituents of Annona muricata. Yao Xue Bao 1997; 32(6): 431–437.
Gleye, C., A. Lauren, R. Hocquemiller, A. Cave, O. Laprevote and L. Serani. Isolation of monte-cristin, a key metabolite in biogenesis of acetogenins from Annona muricata and its structure elucidation by using tandem Mass Spectrometry. J Org Chem 1997; 62(3): 510–513.
Yu, J. G., H. Q. Gui, X. Z. Luo and L. Sun. Murihexol, a linear acetogenin from Annona muricata. Phytochemis’ try 1998; 49(6): 1689–1692.
Bories, C., P. Loiseau, D. Cortes, S. H. Myint, R. Hocquemiller, P. Gayral, A. Cave and A. Laurens. Antiparasitic activity of Annona muricata and Annona cherimolia seeds. Planta Med 1991; 57(5): 434–436.
Lopez Abraham, A. M., N. M. Rojas Hernandez and C. A. Jimenez Misas. Plant extracts with cytostatic properties growing in Cuba. I. Rev Cubana Med Trop 1979; 31(2): 97–104.
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Ross, I.A. (2003). Annona muricata. In: Medicinal Plants of the World. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-365-1_5
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