Abstract
Taurine is present in relatively high (mM) concentrations in mammalian tissues, including the brain. Despite extensive studies of its synthesis, release in response to nerve stimulation and possible neuronal or extraneuronal uptake there is still no consensus about its functions (9,8,12). It has variously been designated as a neurotransmitter, neuromodulator, a modulator of calcium fluxes, and also as an osmoregulator or membrane stabilizer and an antioxidant. These effects may, at least in some cases, be interlinked. Thus, for example, the “neuroprotective” effects of taurine may be related to the osmoregulatory, antioxidant and calcium ion modulating functions of taurine.
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Sgaragli, G., Frosini, M., Palmi, M., Bianchi, L., Corte, L.D. (1994). Calcium and Taurine Interaction in Mammalian Brain Metabolism. In: Huxtable, R.J., Michalk, D. (eds) Taurine in Health and Disease. Advances in Experimental Medicine and Biology, vol 359. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1471-2_30
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DOI: https://doi.org/10.1007/978-1-4899-1471-2_30
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