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Immunochemistry of Variants of Influenza Virus Hemagglutinin and Neuraminidase

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Immunobiology of Proteins and Peptides—III

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 185))

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Abstract

Influenza is impossible to control by vaccination because of variation in the two surface antigens of the virus, the hemagglutinin (HA) and neuraminidase (NA). This variation is caused by sequence changes in the genes coding these antigens and this article summarizes recent information on the structure of the HA and NA, the way in which these glycoproteins vary and the effects of the changes on the antigenic properties of the virus.

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Author information

Authors and Affiliations

  1. John Curtin School of Medical Research, P.O. Box 334, Canberra, Act, 2601, Australia

    W. G. Laver

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  1. W. G. Laver
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Editor information

Editors and Affiliations

  1. Baylor College of Medicine, Houston, Texas, USA

    M. Zouhair Atassi

  2. United States Department of Agriculture, Plum Island, New York, USA

    Howard L. Bachrach

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© 1985 Plenum Press, New York

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Laver, W.G. (1985). Immunochemistry of Variants of Influenza Virus Hemagglutinin and Neuraminidase. In: Atassi, M.Z., Bachrach, H.L. (eds) Immunobiology of Proteins and Peptides—III. Advances in Experimental Medicine and Biology, vol 185. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7974-4_10

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  • DOI: https://doi.org/10.1007/978-1-4684-7974-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-7976-8

  • Online ISBN: 978-1-4684-7974-4

  • eBook Packages: Springer Book Archive

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