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Translational Regulation in Bacteriophages

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Translational Regulation of Gene Expression

Abstract

In Escherichia coli, different translational initiation sites can vary 1000-fold in their intrinsic efficiencies.1,2 These differences are attributable to specific sequence features that are involved in ribosome-messenger (mRNA) interactions as well as to mRNA secondary structures that can inhibit ribosome binding. In addition to the variation in intrinsic strengths of different initiation sites, some sites are subject to regulation so that their efficiencies are modulated according to the state of the cell. For the purposes of this chapter, translational regulation means the action of a gene product that affects the rate of translational initiation for some protein. Other posttranscriptional effects on rates of translation, such as differential mRNA degradation and translational coupling, are not included.

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Authors and Affiliations

  1. Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado, 80309, USA

    Gary D. Stormo

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  1. Gary D. Stormo
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Editors and Affiliations

  1. Department of Developmental Genetics and Anatomy, School of Medicine, Case Western Reserve University, Cleveland, Ohio, 44106, USA

    Joseph Ilan

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© 1987 Plenum Press, New York

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Stormo, G.D. (1987). Translational Regulation in Bacteriophages. In: Ilan, J. (eds) Translational Regulation of Gene Expression. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5365-2_2

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  • DOI: https://doi.org/10.1007/978-1-4684-5365-2_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5367-6

  • Online ISBN: 978-1-4684-5365-2

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