Abstract
In single skeletal muscle fibres treated with low concentration of caffeine, lowering the bathing solution temperature from 18°C to below 7°C increased [Ca2+]i in three phases depending on caffeine concentration and temperature. Tension could be fully developed (rapid cooling contracture, RCC) by the second phase of the released Ca2+. The second and third phases were inhibited by low concentrations of procaine, and the first phase was blocked by a higher one. RCC was observed even in Ca2+-free solution. The mechanism of [Ca2+]i changes and RCC during cooling was discussed.
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© 1984 Plenum Press, New York
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Kurihara, S., Konishi, M., Sakai, T. (1984). Changes in [Ca2+]i Induced by Rapid Cooling of Single Skeletal Muscle Fibres Treated with Low Concentration of Caffeine. In: Pollack, G.H., Sugi, H. (eds) Contractile Mechanisms in Muscle. Advances in Experimental Medicine and Biology, vol 37. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-4703-3_50
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DOI: https://doi.org/10.1007/978-1-4684-4703-3_50
Publisher Name: Springer, Boston, MA
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