Abstract
The majority of particulate high-affinity receptors for LH in the steroidogenic cells of the testis and ovary are membrane-bound and capable of functional coupling to adenylate cyclase(1,2). The gonadal receptors for LH can be solubilized together with adenylate cyclase by a variety of non-ionic detergents(3). In addition to the membrane-associated receptors that require detergent for solubilization, the luteinized ovary has been found to contain a small proportion of spontaneously “soluble” receptor sites (up to 10%) that can be recovered in the floating lipid fraction of the 360,000 x g supernate prepared from ovarian homogenates (4).
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© 1979 Plenum Press, New York
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Dufau, M.L., Hayashi, K., Sala, G., Baukal, A., Catt, K.J. (1979). Gonadal LH Receptors: Resolution from Adenylate Cyclase and Transfer to Heterologous Cells. In: Channing, C.P., Marsh, J.M., Sadler, W.A. (eds) Ovarian Follicular and Corpus Luteum Function. Advances in Experimental Medicine and Biology, vol 112. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3474-3_4
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DOI: https://doi.org/10.1007/978-1-4684-3474-3_4
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