Abstract
This report is divided into two parts. The first is concerned with the binding of 2,3-diphosphoglycerate (DPG) to deoxy- and oxyhemoglobin in the absence and presence of CO2 under conditions comparable to those prevailing in intact erythrocytes. In the second part an attempt is made to analyze the mechanism by which glycolysis is inhibited in erythrocytes containing elevated concentrations of DPG.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Kilmartin, J.V., L. Rossi-Bernardi: Physiol. Rev. 53: 836–890 (1973)
Arnone, A.: Ann.Rev.Med. 25:123–130 (1974)
Bauer, C.: Rev.Physiol.Biochem.Pharmacol. 70:1–31 (1974)
Duhm, J., E. Gerlach: In: The Human Red Cell in Vitro (T. Greenwalt, G.A. Jamieson, eds.), Grune and Stratton, New York-London, pp. 111–148 (1974)
Chanutin, A., E. Herman: Arch.Biochem.Biophys. 131:110–115 (1969)
Luque, J., D. Diederich, S. Grisolia: Biochem.Biophys. Res.Commun. 36:1019–1023 (1969)
Benesch, R.E., R. Benesch, C.I. Yu: Biochemistry 8: 2567–2571 (1969)
Benesch, R.E., R. Benesch, R. Renthal, W.B. Gratzer: Nature New Biology 234:174–176 (1971)
Bunn, F.H., B.J. Ransil, A. Chao: J.Biol.Chem. 246: 5273–5279 (1971)
Garby, L., C.-H. DeVerdier: Scand.J.Clin.Lab.Invest. 27:345–350 (1971)
Caldwell, P.R.B., R.L. Nagel, E.R. Jaffe: Biochem.Biophys. Res.Commun. 44:1504–1509 (1971)
Bauer, Ch.: Resp.Physiol. 10:10–19 (1970)
Duhm, J.: In: Erythrocyte Structure and Function (G. Brewer,ed.), IIIrd International Conference, Ann Arbor, Oct. 16–19, 1974. A.R.Riss, New York (in press)
Berger, H., G.-R. Jänig, G. Gerber, K. Ruckpaul, S.M. Rapoport: Eur.J.Biochem. 38:553–562 (1973)
Hamasaki, N., Z.B. Rose: J.Biol.Chem: 249:7896–7901 (1974)
Rose, I.A.: Exp.Eye Res. 11:264–272 (1971)
Gerber, G., H. Berger, G.-R. Jänig, S.M. Rapoport: Eur.J.Biochem. 38:563–571 (1973)
Wyman, J.: Advanc. Protein Chem. 4:407–531 (1948)
Wyman, J.: Advanc. Protein Chem. 19:223–286 (1964)
Brewer, G.J.: Biochim.Biophys.Acta 192:157–161 (1969)
Ponce, J., S. Roth, D.R. Harkness: Biochim.Biophys.Acta 250:63–74 (1971)
Beutler, E., F. Matsumoto, E. Guinto: Experientia 30: 190–192 (1974)
Keitt, A.S.: Clin.Res. 19:40(Abstract) (1971)
Duhm, J.: Pflügers Arch. 326:341–356 (1971)
Salhany, J.M., A.S. Keitt, R.S. Eliot: Febs Letters 16: 257–261 (1971)
Duhm, J.: In: Oxygen Transport to Tissue, Adv.Exp.Med. Biol. Vol 37A, Plenum Press, New York-London, pp. 179–186 (1973)
Deuticke, B., J. Duhm, R. Dierkesmann: Pflügers Arch. 326:15–34 (1971)
Duhm, J.: Biochim.Biophys.Acta (in press)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Plenum Press, New York
About this chapter
Cite this chapter
Duhm, J. (1976). Effects of 2,3-Diphosphoglycerate on Functional Properties of Hemoglobin and on Glycolysis of Human Erythrocytes. In: Grote, J., Reneau, D., Thews, G. (eds) Oxygen Transport to Tissue — II. Advances in Experimental Medicine and Biology, vol 75. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3273-2_11
Download citation
DOI: https://doi.org/10.1007/978-1-4684-3273-2_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3275-6
Online ISBN: 978-1-4684-3273-2
eBook Packages: Springer Book Archive