Abstract
For about the past 15 years, we have been involved in an experimental approach to the study of the neuroendocrine motor system of the brain which views the many interdependent neuroendocrine systems on as broad a scope as possible. Figure 1 presents a schematic view of the assemblage of the principal neuroendocrine systems known at the present time. When we began our studies during the 1950’s, interest in neuroendocrine regulation was heavily concentrated on just two systems, the pituitary-adrenal cortical and sympathetic-adrenal medullary systems. The view was steadily emerging in endocrinology, however, that the hormones of the various glands are highly interdependent in their metabolic effects throughout the body, being variously aligned in patterns of antagonistic, synergistic, or additive relationships with each other. No single hormone acts entirely alone in isolation. Houssay, among others, has emphasized that there is always a balance between opposing and cooperating hormones acting on any particular metabolic process (Houssay, 1957). Our guiding working hypothesis has been, therefore, that if hormones are so closely interdependent in their actions at the metabolic level, then it seems logical that the integrative mechanisms controlling endocrine secretion are organized in a manner closely in keeping with such interdependencies and that the secretion of the many hormones probably is accordingly coordinated on an overall basis (Mason, 1968c).
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Frankenhaeuser, M., Post, B., Nordheden, B., and Sjoeberg, H. (1969). Physiological and subjective reactions to different physical work loads. Percept. Mot. Skills, 28, 343–349.
Hartley, L. H., Mason, J. W., Hogan, R. P., Jones, L. G., Kotchen, T. A., Mougey, E. H., Wherry, F. E., Pennington, L. L., and Ricketts, P. T. (1912a). Multiple hormonal responses to prolonged exercise in relation to physical training. J. Appl. Physiol. 33, 607–610.
Hartley, L. H., Mason, J. W., Hogan, R. P., Jones, L. G., Kotchen, T. A., Mougey, E. H., Wherry, F. E., Pennington, L. L., and Ricketts, P. T. (1972b). Multiple hormonal responses to graded exercise in relation to physical training. J. Appl. Physiol. 33, 602–606.
Houssay, B. C. (1957). Comments in Hormonal Regulation of Metabolism. Springfield, Ill.: Thomas, p. 27.
Mason, J. W. (1968b). Organization of psychoendocrine mechanisms. Psychosom. Med. 30, 565–808.
Mason, J. W. (1968b). Organization of the multiple endocrine responses to avoidance in the monkey. Psychosom. Med. 30, 774–790.
Mason, J. W. (1968c). “Over-all” hormonal balance as a key to endocrine organization. Psychosom. Med. 30, 791–808.
Mason, J. W. (1971). A Re-evaluation of the concept of “non-specificity” in stress theory. J. Psychiat. Res. 8, 323–333.
Mason, J. W. (1974). Specificity in the organization of neuroendocrine response profiles. In Frontiers in Neurology and Neuroscience Research (P. Seeman and G. Brown, Eds.). Toronto: Univ. of Toronto, pp. 68–70.
Mason, J. W. (1975a). Emotion as reflected in patterns of endocrine integration. In Emotions—Their Parameters and Measurement (L. Levi, Ed.). New York: Raven Press, pp. 143–181.
Mason, J. W. (1975b). A historical view of the stress field, Part I. J. Human Stress 1(1); 6–12.
Mason, J. W. (1975c). A historical view of the stress field, Part II. J. Human Stress 1(2); 22–36.
Mason, J. W. (1975d). Clinical psychophysiology: Psychoendocrine mechanisms. In American Handbook of Psychiatry (M. Reiser, Ed.).
Mason, J. W. (1975e). Psychological stress and endocrine function. In Topics in Psychoendocrinology (E. J. Sachar, Ed.). New York: Grune and Stratton.
Mason, J. W., Hartley, L. H., Kotchen, T. A., Mougey, E. H., Ricketts, P. T., and Jones, L. G. (1973). Plasma cortisol and norepinephrine responses in anticipation of muscular exercise. Psychosom Med. 35, 406–414.
Miller, R. E., and Mason, J. W., (1965). Changes in 17-hydroxycorticosteroid excretion related to increased muscular work. Symposium on Medical Aspects of Stress in the Military Climate, WRAIR. GPO, Washington, D.C.: GPO, pp. 353–372.
Miller, R. E., and Mason, J. W. Unpublished observations.
Poe, R. O., Ehle, A. L., and Mason, J. W. Unpublished observations.
Selye, H. (1936). A syndrome produced by diverse nocuous agents. Nature 138, 32.
Selye, H. (1950). The Physiology and Pathology of Exposure to Stress. Montreal: ACTA, Inc.
Selye, H. (1956). The Stress of Life. New York: McGraw-Hill Book Co.
Selye, H. (1973). The evolution of the stress concept. Am. Sci. 61, 692–699.
Selye, H. (1974). Stress without Distress. Philadelphia: J. B. Lippincott Co.
Selye, H., and Heuser, G. (1956). 5th Annual Report of Stress. New York: MD Publications, Inc.
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Mason, J.W., Mougey, E.H., Perlow, M.J., Maher, J.T., Hartley, L.H., Jones, L.G. (1976). Selectivity of Corticosteroid and Catecholamine Responses to Various Natural Stimuli. In: Serban, G. (eds) Psychopathology of Human Adaptation. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2238-2_10
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DOI: https://doi.org/10.1007/978-1-4684-2238-2_10
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