Abstract
Recent comparative studies of receptor-gated membrane channels show that there may exist wide variations in channel gating kinetics between different types of receptors found in the membranes of excitable cells. Studies of nicotinic acetylcholine receptors have led to the conclusion that channel gating follows a sequential scheme (e.g. Colquhoun and Sakmann, 1980) of the type predicted many years ago from macrosysem studies on vertebrate skeletal nerve muscle junctions (Katz and Miledi, 1972), although more complex models have been suggested for this system (e.g. Jackson et al., 1983; Labarca et al., 1985). In this paper I review the literature on a glutamate receptor channel of locust muscle for which a model based upon that for allosteric enzymes has been proposed (Monod et al., 1965).
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References
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© 1988 Plenum Press, New York
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Usherwood, P.N.R. (1988). Locust Muscle Glutamate Receptors — Support for an Allosteric Model. In: Markov, M., Blank, M. (eds) Electromagnetic Fields and Biomembranes. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-9507-6_11
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DOI: https://doi.org/10.1007/978-1-4615-9507-6_11
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