Abstract
As the body’s first line of defense against external insult, both the eye and the skin are exposed routinely to chemical agents, serving as a portal of entry for topical contactants. In addition, global atmospheric changes like ozone depletion in the stratosphere contribute to enhanced chronic exposure of the skin and the eye of human tissue to UV light (Hendee, 1989). The hazardous effects of UV light on the eye were already recognized in 1920 by van der Hoeve. By the 1920s, basal cell carcinomas of the skin were also noted.
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Pappas, P., Stephanou, P., Vasiliou, V., Karamanakos, P., Marselos, M. (1996). Ontogenesis and Expression of ALDH Activity in the Skin and the Eye of the Rat. In: Weiner, H., Lindahl, R., Crabb, D.W., Flynn, T.G. (eds) Enzymology and Molecular Biology of Carbonyl Metabolism 6. Advances in Experimental Medicine and Biology, vol 414. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5871-2_10
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