Abstract
The human menisci and intervertebral discs perform several important mechanical functions in the human body. The ability to perform these functions and consequently their intrinsic biomechanical properties are dependent on the interaction of the constituents of these structures. Both the menisci and intervertebral discs have a fibrocartilaginous structure that consists of two distinct phases: a fluid phase consisting of mainly water and dissolved electrolytes, and a solid phase composed of highly oriented collagen fibers, cells, proteoglycans and other proteins. As with all other biological materials, both menisci and discs exhibit non-linear viscoelastic and anisotropic properties. The non-linear stiffness or elasticity of the structure is imparted by the collagen fibers and to a lesser extent by osmotic pressures within the tissue which are generated by the degree of hydration [1, 2]. The viscoelastic or energy dissipation properties are a result of fluid flow within and through the structures and also of molecular relaxation effects from the motion of long chains of collagen and proteoglycans [3]. Anisotropy is a consequence of the orientation and concentration of collagen fibers within the proteoglycan gel.
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References
Armstrong, C.G. and Mow, V.C. (1982) Variations in the intrinsic mechanical properties of human articular cartilage with age, degeneration and water content. J. Bone Joint Surg., 64A, 88–94.
Mow, V.C, Hohnes, M.H. and Lai, W.M. (1984) Fluid transport and mechanical properties of articular cartilage: A review. J. Biomech., 102, 73–84.
Hayes, W.C and Bodine, A.J. (1978) Flow independent viscoelastic properties of articular cartilage matrix. J. Biomech., 11, 407–419.
Mathur, P.D., McDonald, J.R. and Ghormley, R.K. (1949) A study of the tensile strength of the menisci of the knee. J. Bone Joint Surg., 32A, 650–654.
Aspden, R.M., Yarker, Y.E. and Hukins, D.W.L. (1985) Collagen Orientations in the meniscus of the knee joint. J. Anat., 140, 371–380.
Bullough, P.G., Munuera, L., Murphy, J. and Weinstein, A.M. (1970) The strength of the menisci of the knee as it relates to their fine structure. J. Bone Joint Surg., 52B, 564–570.
Fithian, D.C., Kelly, M.A. and Mow, V.C (1990) Material properties and structure-function relationships in the menisci. Clin. Orthop. Rel. Res., 252, 19–31.
Mow, V.C, Zhu, W. and Ratcliffe, A. (1991) Structure and function of articular cartilage and meniscus, in Basic Orthopaedic Biomechanics, (eds V.C Mow and W.C Hayes), Raven Press, New York, pp. 143–198.
Eyre, D.R. and Wu, J.J. (1983) Collagen of fibrocartilage: A distinctive molecular phenotype in bovine meniscus. F. E. B. S. Letters, 158, 265–270.
Fithian, D.C, Zhu, W.B., Ratcliffe, A., Kelly, M.A. and Mow, V.C. (1989b) Exponential law representation of tensile properties of human meniscus. Proceedings of the Institute of Mechanical Engineers. The Changing Role of Orthopaedics, Mechanical Engineering Publications Limited, London, pp. 85–90
Ghosh, P. and Taylor, T.K.F. (1987) The knee joint meniscus: A fibrocartilage of some distinction. Clin. Orthop. Rel Res., 224, 52–63.
Ingman, A.M., Ghosh, P. and Taylor, T.K.F. (1974) Variation of collagenous and non-collagenous proteins of human knee joint menisci with age and degeneration. Gerontology, 20, 212–223.
Pooni, J.S., Hukins, D.W.L., Harris, P.F., Hilton, R.C and Davies, K.E. (1986) Comparison of the structure of human intervertébral discs in the cervical, thoracic and lumbar regions of the spine. Surg. Radiol. Anat, 8, 175–182.
Hirsch, C, Inglemark, B-H. and Miller, M. (1963) The anatomical basis of back pain. Acta Orthop. Scand., 33, 2–17.
Lin, H.S., Liu, Y.K. and Adams, K.H. (1978) Mechanical response of the lumbar intervertebral joint under physiological (complex) loading. J. Bone Joint Surg., 60A, 41–55.
Lin, H.S., Liu, Y.K., Ray, G. and Nikravesh, P. (1978) System identification for material properties of the intervertebral joint. J. Biomech., 11, 1–14.
Taylor, J.R. (1975) Growth of human intervertebral discs and vertebral bodies. J. Anat, 120, 49–68.
Panjabi, M.M., Summers, DJ., Pelker, R.R., Videman, T., Friedlander, G.E. and Southwick, W.O. (1986) Three-dimensional load-displacement curves due to forces on the cervical spine. J. Ortho. Res., 4, 152–161.
Inoue, H. (1981) Three-dimensional architecture of lumbar intervertebral discs. Spine, 6, 139–146.
Panagiotacopulos, N.D., Knauss, W.G. and Bloch, R. (1979) On the mechanical properties of human intervertebral disc materials. Biorheology, 16, 317–330.
Marchand, F. and Ahmed, A.M. (1988) Investigation of the laminate structure of lumbar disc annulus fibrosus. Trans. Orthop. Res. Soc, 13, 271.
Best B.A., Guilak, F., Setton, L.A., Zhu, W., Saed-Nejad, F., Ratcliffe, A., Weidenbaum, M. and Mow, V.C. (1994) Compressive mechanical properties of the human annulus fibrosus and their relationship to biochemical composition. Spine, 19, 212–221.
Gower, W.E. and Pedrini, V. (1969) Age-related variations in protein-poly-saccharide from human nucleus pulposus, annulus fibrosus and costal cartilage. J. Bone Joint Surg., 51A, 1154–1162.
Lyons, G., Eisenstein, S.M. and Sweet, M.B.E. (1981) Biochemical changes in intervertebral disc degeneration, Biophysics Acta, 673, 443.
Lai, W.M. and Mow, V.C. (1980) Drag-induced compression of articular cartilage during a permeation experiment. Biorheology, 17, 111–123.
Proctor, C.S., Schmidt, M.B., Whipple, R.R., Kelly, M.A. and Mow, V.C. (1989) Material Properties of the normal medial bovine meniscus. J. Ortho. Res., 7, 771–782.
Eberhardt, A.W., Keer, L.M., Lewis, J.L. and Vithoontien, V. (1990) An analytical model of joint contact. J. Biomech. Eng., 112, 407–413.
Fithian D.C., Schmidt, M.B., Ratcliffe, A. and Mow, V.C. (1989a) Human meniscus tensile properties: Regional variation and biochemical correlation. Trans. Orthop. Res. Soc, 14, 205.
Brown, T., Hansen, R.J. and Torra, AJ. (1957) Some mechanical tests on the lumbosacral spine with particular reference to the intervertebral discs. J. Bone Joint Surg., 39A, 1135–1164.
Hirsch, C. and Nachemson, A. (1954) New observations on the mechanical behavior of the lumbar discs. Acta Orthop. Scand., 23, 254–283.
Schultz, A.B., Warwick, D.N., Berkson, M.H. and Nachemson, A.L. (1979) Mechanical properties of human lumbar spine motion segments Part I. J. Biomech. Eng., 101, 46–52.
Berkson, M.H., Nachemson, A. and Schultz, A.B. (1979) Mechanical properties of human lumbar spine motion segments Part I. J. Biomech. Eng., 101,53–57.
Marchand, F. and Ahmed, A.M. (1989) Mechanical properties and failure mechanisms of the lumbar disc annulus. Trans. Orthop. Res. Soc, 14, 355.
Galante, J.O. (1967) Tensile properties of the human lumbar annulus fibrosus. Acta Orthop. Scand., (Suppl. 100), 1–91.
Chern, K.Y., Zhu, W.B. and Mow, V.C. (1989) Anisotropic viscoelastic shear properties of meniscus. Adv. Bioeng., BED-15, 105–106.
Burns, ML. et al. (1984) Analysis of compressive creep behavior of the vertebral unit subjected to uniform axial loading using exact parametric solution equations of Kelvin solid models Part I. J. Biomech., 17, 113–130.
Kazarian, L.E. and Kaleps, I. (1979) Mechanical and physical properties of the human intervertebral joint. Technical Report AMRL-TR-79-3, Aerospace Medical Research Laboratory, Wright Patterson Air Force Base, OH
Black, J. (1976) Dead or alive: The problem of in vitro tissue mechanics. J. Biomed. Mats. Res., 10, 377–389.
Black, J. (1984) Tissue properties: Relation of in vitro studies to in vivo behavior, in Natural and Living Biomaterials, Ed. G.W. Hastings and P. Ducheyne, CRC Press, Boca Raton, pp. 5–26.
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Gharpuray, V.M. (1998). Fibrocartilage. In: Black, J., Hastings, G. (eds) Handbook of Biomaterial Properties. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5801-9_5
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DOI: https://doi.org/10.1007/978-1-4615-5801-9_5
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