Abstract
Soft tissue sarcomas have been defined as malignant tumors involving nonepithelial extraskeletal tissues of the body, exclusive of the reticuloendothelial system, glia, and supporting tissues of various parenchymal organs [1]. The soft tissues are represented by voluntary muscles, fat, and fibrous tissue, along with the vessels servicing these tissues [1]. By convention, the soft tissues include the peripheral nervous system because tumors arising from nerves present as soft tissue masses and pose similar problems in differential diagnosis and therapy [1]. Embryologically, the soft tissues are derived principally from mesoderm, with some contribution for ectoderm [1].
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Pratt, C.B., Kun, L.E. (1991). Soft Tissue Sarcomas of Children. In: Pinedo, H.M., Verweij, J., Suit, H.D. (eds) Soft Tissue Sarcomas: New Developments in the Multidisciplinary Approach to Treatment. Cancer Treatment and Research, vol 56. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3896-7_11
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