Abstract
Small cell osteosarcoma (SCO) is a rare but distinct variant of osteosarcoma. Although Hutter et al. [1] in 1966 and Jacobson in 1977 [2] described small cell tumors of bone capable of differentiating into bone and cartilage, Sim and collaborators [3], reporting in 1979 on 24 patients at the Mayo Clinic, were the first to delineate the clinicopathological features of this entity. Further clarification was given by other investigators [4–7], but few large series of patients with these lesions have been studied [3–7], and there have been only several case reports [8–10] of these lesions.
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Ayala, A.G., Ro, J.Y., Papadopoulos, N.K., Raymond, A.K., Edeiken, J. (1993). Small cell osteosarcoma. In: Humphrey, G.B., Koops, H.S., Molenaar, W.M., Postma, A. (eds) Osteosarcoma in Adolescents and Young Adults: New Developments and Controversies. Cancer Treatment and Research, vol 62. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3518-8_17
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DOI: https://doi.org/10.1007/978-1-4615-3518-8_17
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