Abstract
A number of years ago taurine was recognized as an osmoregulator in marine animals1 and attention has been drawn to its possible participation in cell volume regulation also in terrestial animals.2 It has been suggested that taurine participates in the regulation of extracellular ionic homeostasis in the central nervous system, and in particular, in the active uptake of K+ by astroglial cells.3,4 Recently, some investigators have thought that the role of taurine in the mammalian brain is to act as an osmolyte5,6 which is released as a response to cell swelling.7 Since depolarizing stimuli are known to release taurine from various brain preparations,8,9 this response has been interpreted to ensue from depolarization-induced cell swelling.10
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© 1992 Springer Science+Business Media New York
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Oja, S.S., Saransaari, P. (1992). Cell Volume Changes and Taurine Release in Cerebral Cortical Slices. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_43
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DOI: https://doi.org/10.1007/978-1-4615-3436-5_43
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