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Gas Exchange and Lung Mechanics during Long-Term Mechanical Ventilation with Intratracheal Perfluorocarbon Administration in Respiratory Distress Syndrome

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Oxygen Transport to Tissue XIV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 317))

Abstract

Respiratory distress syndrome (RDS) is mainly characterized by hypoxemia and pronounced alveolar collapse, associated with high surface forces in the alveoli. Several methods of artificial ventilation have been introduced to support such lungs and maintain adequate oxygenation until recovery of lung function occurs [1–5]. Since perfluorocarbon (PFC) liquids were recognized as a useful media for pulmonary gas exchange, animal studies with PFC liquid ventilation have demonstrated that elimination of high surface forces in the PFC-filled lung can offer an alternative respiratory medium to improve gas exchange and lung expansion [6–8].

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Tütüncü, A.S., Akpir, K., Mulder, P., Faithfull, N.S., Erdmann, W., Lachmann, B. (1992). Gas Exchange and Lung Mechanics during Long-Term Mechanical Ventilation with Intratracheal Perfluorocarbon Administration in Respiratory Distress Syndrome. In: Erdmann, W., Bruley, D.F. (eds) Oxygen Transport to Tissue XIV. Advances in Experimental Medicine and Biology, vol 317. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3428-0_45

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  • DOI: https://doi.org/10.1007/978-1-4615-3428-0_45

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6516-7

  • Online ISBN: 978-1-4615-3428-0

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