Abstract
Recent studies using a quantitative image analysis technique (Clarke, Daly & Ead 1990) have shown that the vascular compartment of the carotid body may be analysed with special reference to the vessels whose diameters lie between 5µm and 12µm. It is well known that in the spontaneously hypertensive rat (SHR) the carotid bodies are enlarged (Habeck 1991). Accordingly we have applied this technique to the analysis of the carotid body in these SHR animals to determine the contribution of the vascular compartment to the increase in volume. In this study the volumes of the carotid body and its vascular compartment were studied during postnatal maturation of the control and SHR animals. The vascular compartment was divided into that containing small vessels (diameter 5µm - 12µm) and that containing vessels greater than 12µm in diameter.
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© 1993 Springer Science+Business Media New York
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Clarke, J.A., de Daly, M.B., Ead, H.W. (1993). Vascular Analysis of the Carotid Body in the Spontaneously Hypertensive Rat. In: Data, P.G., Acker, H., Lahiri, S. (eds) Neurobiology and Cell Physiology of Chemoreception. Advances in Experimental Medicine and Biology, vol 337. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2966-8_1
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DOI: https://doi.org/10.1007/978-1-4615-2966-8_1
Publisher Name: Springer, Boston, MA
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