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Microvascular PO2 Regulation and Chemoreception in the Cat Carotid Body

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Oxygen Transport to Tissue XV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 345))

Abstract

Regulation of carotid body microcirculation and microvascular PO2 is in itself of great physiological interest, and understanding their roles in the integrated cellular and sensory functions is critical. Now that a sensitive optical method, based on quenching of phosphorescence of lumiphors is available (Vanderkooi et al., 1987; Wilson et al., 1988), we investigated the effects of arterial PCO2 and PO2 changes on the cat carotid body microvascular PO2 (CBM PO2) simultaneously with the chemosensory activity in vivo. The working hypothesis was that PCO2 -pH changes do not change CBM PO2 but affects the sensory discharge directly.

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© 1994 Springer Science+Business Media New York

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Lahiri, S., Wilson, D.F., Iturriaga, R., Rumsey, W.L. (1994). Microvascular PO2 Regulation and Chemoreception in the Cat Carotid Body. In: Vaupel, P., Zander, R., Bruley, D.F. (eds) Oxygen Transport to Tissue XV. Advances in Experimental Medicine and Biology, vol 345. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2468-7_17

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  • DOI: https://doi.org/10.1007/978-1-4615-2468-7_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6051-3

  • Online ISBN: 978-1-4615-2468-7

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