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Effects of Hypertonic Saline on the Pulmonary Gas Exchange

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Oxygen Transport to Tissue XV

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 345))

Abstract

Hypertonic saline solution (HSS) increases cardiac output (QT) in animals as well as in patients with hypovolemic shock. It has been observed on several occasions that elevations of QT resulted in a concomitant increase of venous admixture (QVA/QT) and/or intrapulmonary shunt (QS/QT).1,2,3 However, Constable et al.4 showed in endotoxemic calves that HSS had no effect on QVA/QT despite an increase of QT. It was the purpose of this study to examine the effect of HSS on QVA/QT in humans with hyperdynamic septic shock.

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References

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© 1994 Springer Science+Business Media New York

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Hannemann, L., Schaffartzik, W., Meier-Hellmann, A., Reinhart, K. (1994). Effects of Hypertonic Saline on the Pulmonary Gas Exchange. In: Vaupel, P., Zander, R., Bruley, D.F. (eds) Oxygen Transport to Tissue XV. Advances in Experimental Medicine and Biology, vol 345. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2468-7_13

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  • DOI: https://doi.org/10.1007/978-1-4615-2468-7_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6051-3

  • Online ISBN: 978-1-4615-2468-7

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