Abstract
Local-regional therapies are those treatment modalities which, by the percutaneous route, allow the introduction of a damaging agent directly into the neoplastic tissue. It is understood that such therapies are indicated only for those pathologies limited to a single organ, like hepatocellular carcinoma (HCC) not in an advanced stage. Local-regional therapies may be based on the use of means capable of destroying the tissue chemically, such as with ethyl alcohol (percutaneous ethanol injection, PEI) or acetic acid, or physically (thermal), as with laser, microwave or radiofrequency (RF). PEI was the first to be proposed (1). On the basis of its rationale and the results obtained, the other therapies were subsequently designed (2-5). This chapter considers mainly PEI, which is the most diffused and codified, and RF therapy, whose recent results indicate a wide development.
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Livraghi, T., Meloni, F. (2002). Percutaneous Ablation Therapy of Hepatocellular Carcinoma. In: Habib, N.A. (eds) Multi-Treatment Modalities of Liver Tumours. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0547-1_12
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DOI: https://doi.org/10.1007/978-1-4615-0547-1_12
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