Skip to main content

Radiofrequency Thermal Ablation of Hepatocellular Carcinoma

  • Chapter
Multi-Treatment Modalities of Liver Tumours

Abstract

Minimally invasive percutaneous therapies, such as percutaneous ethanol injection (PEI) or interstitial hyperthermia obtained by radiofrequency (RF) have now been accepted by many groups as first step treatment of hepatocellular carcinoma (HCC) in cirrhosis’, taking into account the surgical risk and the very high recurrence rate, which are characteristic of this tumour.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Lencioni, R., Bartolozzi, C., 1997, Nonsurgical treatment of hepatocellular carcinoma. Cancer J. 10: 17–23

    CAS  Google Scholar 

  2. Dynlach, J.R., Fox, M.H., 1992, The effect of 45° hyperthemia on the membrane fluidity of cells of several lines. Rad Res 130:55–60.

    Article  Google Scholar 

  3. Rossi, S., Fomari, F., Paties C., Buscarini L., 1990, Thermal lesions induced by 480 KHz localized current field in guinea pig and pig liver. Tumori 7:54–57

    Google Scholar 

  4. Organ, L.W., 1976, Electrophysiologic principles of radiofrequency lesion making. Appl. Neurophysiol. 39: 69–76.

    Google Scholar 

  5. Chang, R.J., Stewenson, W.G., Saxon, L.A., Parker, J., 1993, Increasing catheter ablation lesion size by simultaneous application of radiofrequency current to two adjacent sites. 125: 1276–1284

    Google Scholar 

  6. Buscarini, L., Rossi, S., Di Stasi, M., Buscarini, E., 1996, Percutaneous radio-frequency interstitial thermal ablation of hepatocellular carcinoma. Radiology 201 (P): 267–268

    Google Scholar 

  7. Le Veen, R., 1997, Laser hyperthermia and radiofrequency ablation of hepatic lesions. Semin Intervent Radiol. 14: 313–324

    Google Scholar 

  8. Lorentzen, T., 1996, A cooled needle electrode for radiofrequency tissue ablation: thermodynamic aspects of improved performance compared with conventional needle design. Acad Radiol 3: 556–563

    Article  PubMed  CAS  Google Scholar 

  9. Rossi, S., Buscarini, E., Garbagnati, F., Di Stasi, M., Quaretti, P., Rago, M., et al., 1998, Percutaneous treatment of small hepatic tumors by an expandable RF needle electrode. AJR 170: 1015–1022.

    PubMed  CAS  Google Scholar 

  10. Solbiati, L., Goldberg, SN., lerace, T., Livraghi, T., Meloni, F., Dellanoce, M., et al., 1997, Hepatic metastases: percutaneous radio-frequency ablation with cooled-tip electrodes. Radiology 205: 367–373

    PubMed  CAS  Google Scholar 

  11. Goldberg, S.N., Hahn, P.F., Schima, W., Gazelle, G.S., Solbiati, L., Mueller, P.R., 1996, Percutaneous radiofrequency tissue ablation in the liver: increased coagulation necrosis with portal venous occlusion Radiology 250 (P): 201.

    Google Scholar 

  12. Buscarini, L., 1998, Percutaneous RF interstitial thermal ablation after transarterial embolization for treatment of large hepatic tumors Radiology 209 (P): 266.

    Google Scholar 

  13. Buscarini, L., Rossi, S., 1997, Technology for radiofrequency thermal ablation in liver tumors. Semin Laparoscopie Surg 4: 96–101.

    Google Scholar 

  14. Tucker De Sanctis, J., Goldberg, S.N., Mueller, P.R., 1997, Percutaneous treatment of hepatic neoplasm: a review of current techniques. Semin Intervent Radiol 14: 255–284.

    Article  Google Scholar 

  15. Rhim, H., Dodd, G.D., 1999, Radiofrequency thermal ablation of liver tumors. J Clin Ultrasound 27: 221–229.

    Article  PubMed  CAS  Google Scholar 

  16. Buscarini, L., Rossi, S., Fornari, F., Di Stasi, M, Buscarini, E. 1995, Laparoscopic ablation of liver adenoma by radiofrequency electrocautery. Gastrointest Endoscopy 41: 68–70.

    Article  CAS  Google Scholar 

  17. Siperstein, A.E., Rogers, S.J., Hansen, P.D., Gitomirsky, A., 1997, Laparoscopic thermal ablation of hepatic neuroendocrine tumour metastases. Surgery 122: 1147–1155.

    Article  PubMed  CAS  Google Scholar 

  18. Curley, S.A., Izzo, F., Delrio, Pn., Ellis, M.L., Granchi, J., Vallone, P., et al, 1999, Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies. Results in 123 patients. Ann Surg 230:1–8.

    CAS  Google Scholar 

  19. Buscarini, L., Buscarini, E., Di Stasi, M., Quaretti, P., Zangrandi, A., 1999, Percutaneous radiofrequency thermal ablation combined with transcatheter arterial embolization in the treatment of large hepatocellular carcinoma Ultraschall in Med 20:47–53.

    Article  CAS  Google Scholar 

  20. Rossi, S., Garbagnati, F., Lencioni, R., Allgaier, H.P., Marchianò, A., Fomari, F., et al., 2000, Percutaneous radio-frequency thermal ablation of nonresectable hepatocellular carcinoma after occlusion of tumour blood supply. Radiology 217: 119–126.

    PubMed  CAS  Google Scholar 

  21. Sironi, S., Livraghi, T., Meloni, F., De Cobelli, F., Ferrero, C.G., Del Maschio, A., 1999, Small hepatocellular carcinoma treated with percutaneous RF ablation: RM imaging follow-up. AJR 173: 1225–1229

    PubMed  CAS  Google Scholar 

  22. Lencioni, R., Cioni, D., Bartolozzi, C., 2000, Color Dioppler and contrast media in the evaluation of the treatment of focal liver lesions. Ultrasound Med Biol 26 suppl 2:Al22.

    Google Scholar 

  23. McGahan, J.P., Browning, P.D., Brock, J.M., Tesluk, H., 1990, Hepatic ablation using radiofrequency electrocautery. Invest Radiol 25: 267–270

    Article  PubMed  CAS  Google Scholar 

  24. Buscarini, L., Fomari, F., Rossi, S., 1992, Interstitial radiofrequency hyperthermia in the treatment of small hepatocellular carcinoma: percutaneous sonography-guidance of electrode needle. In Ultraschall-Diagnostik 91. (Anderegg A, Despland PA, Otto R, Henner H, eds.), Springer-Verlag, Berlin, pp. 218–222.

    Google Scholar 

  25. Rossi, S, Di Stasi, M, Buscarini, E, Quaretti, P, Garbagnati, F., Squassante, L., et al., 1996 Percutaneous RF interstitial thermal ablation in the treatment of hepatic cancer. AJR 167: 759–768.

    PubMed  CAS  Google Scholar 

  26. Buscarini, L., Buscarini, E., Di Stasi, M., Vallisa, D., Quaretti, P., Rocca, A., 2000, Percutaneous Radiofrequency ablation of small hepatocellular carcinoma. Long term results. Eur Radiol in press

    Google Scholar 

  27. Livraghi, T., Goldberg, S.N., Lazzaroni, S., Meloni, F., Ierace, T., Solbiati, L., et al, 2000, Hepatocellular carcinoma: Radio-frequency ablation of medium and large lesions. Radiology 214:761–768.

    PubMed  CAS  Google Scholar 

  28. Lencioni, R., Cioni, D., Paolicchi, A., Armillotta, N., Donati, F., Bartolozzi, C., 1998, Percutaneous treatment of small hepatocellular carcinoma: radiofrequency thermal ablation versus percutaneous ethanol injection - A prospective, randomized trial (2nd report). Radiology 209 (P): 174

    Google Scholar 

  29. Livraghi, T., Goldberg, S.N., Lazzaroni, S., Meloni, F., Solbiati, L, Gazelle, G.S., 1999, Small hepatocellular carcinoma: treatment with radio-frequency ablation versus ethanol injection. Radiology 210: 655–661.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer Science+Business Media New York

About this chapter

Cite this chapter

Buscarini, L., Buscarini, E. (2002). Radiofrequency Thermal Ablation of Hepatocellular Carcinoma. In: Habib, N.A. (eds) Multi-Treatment Modalities of Liver Tumours. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0547-1_10

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-0547-1_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5126-9

  • Online ISBN: 978-1-4615-0547-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics