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In Vivo Measurement of Oxygen Pressure Using 19F-NMR Imaging

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Oxygen Transport to Tissue XVII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 388))

Abstract

Nuclear magnetic resonance (NMR) of the fluorine nucleus is an in vivo method to measure non-invasively oxygen pressures. The measurement is based on the effect that the longitudinal relaxation rate (R1 = 1/T1) increases linearly with the partial oxygen pressure (pO2) when the temperature is kept constant [1,2]:

$$R_1 = 1/T_1 = A + B \times pO_2 $$
(1)

The calibration constants A and B depend strongly on temperature, magnetic field strength, the fluorinated subtances, the resonance line used for imaging, and on the tissue type

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© 1996 Plenum Press, New York

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Lutz, J., Nöth, U., Morrissey, S.P., Adolf, H., Deichmann, R., Haase, A. (1996). In Vivo Measurement of Oxygen Pressure Using 19F-NMR Imaging. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_6

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  • DOI: https://doi.org/10.1007/978-1-4613-0333-6_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8002-3

  • Online ISBN: 978-1-4613-0333-6

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